“…At SMF diagnosis, we did not find any correlation between BMF grade and age, gender, time to progression from PV/ET, spleen and liver size, presence of constitutional symptoms and marrow blast percentage (Table S1). No relationship was noticed with abnormal karyotype (stratified as previously reported) 6 with data available in about 50% of the cohort (Table S1). Looking at genotype, BMF grading was not differently distributed among the three driver mutations as well as in "triple negative" cases (Table S1).…”