Bone marrow aplasia associated with metronidazole.

Abstract

The Samson infant resuscitator2 may be preferable, since although high transitory pressures may be achieved the smaller reservoir does not allow maintenance of this high pressure. The question is what to recommend for the relatively inezperienced person and there is a need for existing apparatus to be critically appraised.

A Case of Aplastic Anemia Associated With Long-Term Metronidazole Use

“…Only one other case of metronidazole-induced aplastic anemia has been described in literature. 6 White and colleagues reported a case in which a 74-year-old male received metronidazole 200 mg orally 3 times daily for 7 days prior to a right hemicolectomy and for 10 days post-procedure. The patient developed fluctuating pyrexia for 11 days post-procedure and further workup demonstrated bone marrow aplasia.…”

Metronidazol tedavisine bağlı olarak lökopeni ve trombositopeni gelişen akut gastroenterit olgusu

“…Metronidazole bağlı olarak sık bildirilen yan etkilerin başlıcaları bulantı, diyare, kuru ağız, dilde metalik tat, stomatit, periferik nöropati ve alkolle birlikte alındığında disülfiram benzeri yan etkidir [2][3][4][5] .Bu yan etkiler olguların %2-10'unda görülür [4]. Metronidazole bağlı olarak hematolojik yan etkiler ise lökopeni, nötropeni, trombositopeni, pansitopeni ve Hemolitik Üremik Sendromu içerir [6][7][8][9][10][11][12]. Nadir görülen yan etkileri içerisinde ise Stevens-Johnson Sendromu, pankreatit, oftalmik toksisite ve ototoksisite yer alır [4].…”