Bone in intestinal polyp-a curious observation

Abstract

We report rare phenomena of ossification in benign colon polyp. An adult woman presented with occasional bleeding per rectum for which she was investigated. A polypoid rectal swelling was detected and histolopathology revealed an inflammatory polyp with osteoid formation. The case is presented for its rarity and available literature is reviewed. DOI: http://dx.doi.org/10.3329/bjms.v12i4.16669 Bangladesh Journal of Medical Science Vol. 12 No. 04 October ’13 Page 453-455

Juvenile rectal polyp with osseous metaplasia- A rare case report.

“…BMP 2 and BMP4 were noted in stromal fibroblasts [1]. In inflammatory polyps, persistent inflammation resulted in osteogenic stimulation suggesting that inflammation plays an important role in benign polypoidal lesions [5,9].…”

“…The majority of cases were in the colon, the most common site being the rectum (21/52 cases). Histologically the malignant lesions with osseous metaplasia were commonly seen with the presence of mucin extravasation [5,12].…”

“…There are only few case reports of neoplastic and non neoplastic gastrointestinal polyps with osseous metaplasia [2,3]. An electronic literature search undertaken revealed only eight cases of juvenile colonic polyps with osseous metaplasia and fourteen cases of other morphological types of colorectal polyps with bone formation [4,5]. Though occurrence of bone in the polyp is an incidental finding and does not have any clinical or prognostic significance, the mechanism of bone formation is still a topic of significant debate [2].…”