Bone-implant degradation and mechanical response of bone surrounding Mg-alloy implants

Meischel, Martin; Hörmann, Daniel; Draxler, Johannes; Tschegg, E. K.; Eichler, Jens; Prohaska, Thomas; Stanzl-Tschegg, Stefanie E.

doi:10.1016/j.jmbbm.2017.03.025

Cited by 26 publications

(17 citation statements)

References 18 publications

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“…An unimplanted bone was used as a reference. The study revealed that the hardness of the bone was affected by the initial degradation of implants and then reached at the same level as a reference after the complete degradation confirming no adverse effects on the mechanical strength of bones …”

Section: Current Biomedical Applications Of Mgmentioning

confidence: 71%

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The current trends of Mg alloys in biomedical applications—A review

2018

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Magnesium (Mg) has emerged as an ideal alternative to the permanent implant materials owing to its enhanced properties such as biodegradation, better mechanical strengths than polymeric biodegradable materials and biocompatibility. It has been under investigation as an implant material both in cardiovascular and orthopedic applications. The use of Mg as an implant material reduces the risk of long-term incompatible interaction of implant with tissues and eliminates the second surgical procedure to remove the implant, thus minimizes the complications. The hurdle in the extensive use of Mg implants is its fast degradation rate, which consequently reduces the mechanical strength to support the implant site. Alloy development, surface treatment, and design modification of implants are the routes that can lead to the improved corrosion resistance of Mg implants and extensive research is going on in all three directions. In this review, the recent trends in the alloying and surface treatment of Mg have been discussed in detail. Additionally, the recent progress in the use of computational models to analyze Mg bioimplants has been given special consideration.

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Section: Current Biomedical Applications Of Mgmentioning

confidence: 71%

“…The recent research in the field of Mg and its alloys revolves around two main applications: vascular stents and orthopedics . The first successful implantation of a biodegradable Mg stent became possible in 2005 when it was implanted in treating a left pulmonary artery of a 6 week old baby .…”

Section: Current Biomedical Applications Of Mgmentioning

confidence: 99%

The current trends of Mg alloys in biomedical applications—A review

2018

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“…showed that the complex load situation in bone creates a nanostructural response in all three dimensions [50] depending on the orientation with respect to the anatomy, and in the case of implants on their type and implant placement [14]. Recent developments in analytical techniques strived to solve this problem by developing methods suitable for 3D investigations of nanostructured materials.…”

Section: Discussionmentioning

confidence: 99%

3D nanoscale analysis of bone healing around degrading Mg implants studied by X-ray scattering tensor tomography

Liebi

Lutz‐Bueno

Guizar‐Sicairos

et al. 2020

Preprint

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The nanostructural adaptation of bone is crucial for its compatibility with orthopedic implants. The bone’s nanostructure determines its mechanical properties, however little is known about its temporal and spatial adaptation in degrading implants. This study presents insights into this adaptation by applying electron microscopy, elemental analysis, and small-angle X-ray scattering tensor-tomography (SASTT). We extend the SASTT reconstruction to multiple radii of the reciprocal space vector q, providing a 3D reciprocal-space map per voxel. Each scattering curve is spatially linked to one voxel in the volume, and properties such as the thickness of the mineral particles are quantified. This reconstruction provides information on nanostructural adaptation during healing around a degrading ZX10 magnesium implant over the course of 18 months, using a sham as control. The nanostructural adaptation process is observed to start with an initially fast interfacial organization towards the implant direction, followed by a substantial reorganization of the volume around the implant, and an adaptation in the later degradation stages. The study sheds light on the complex bone-implant interaction in 3D, allowing a more guided approach towards the design of future implant materials, which are expected to be of great interest for further clinical studies on the bone-implant interaction.TOC text and figureDegrading Magnesium implants are mechanically and chemically well adapted orthopedic implant materials and ensure a gradual load transfer during bone healing due to their degradation. The impact of the implant degradation on the bone nanostructure is however not fully understood. This study unveils the processes 3D and shows different stages of bone healing.

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“…Agar temperatur tidak naik drastis biasanya terdapat metal bearing yang dialiri pelumas agar suhu tetap dingin karena diminimalisir gesekannya dan didinginkan (Ramesh et al, 2018). Bersama itu sistem ini membentuk mekanisme yang mana merubah gerak lurus linear manjadi gerak melingkar atau berputar (Wu et al, 2017 (Meischel et al, 2017). Selanjutnya dari segi penggunaan Ti Alloy penggunaanya lebih banyak pada komponen pesawat yang mana memerlukan struktur dan sifat material yang padat dan rapat sehingga kuat dan tidak mudah patah berbeda dengan Al Alloy yang mana penggunaannya sering digunakan pada komponen velg dan bodi kendaraan karena sifatnya yang ringan (Hutař et al, 2017).…”

Section: Gambar 2 Desain 2 Dimensi Batang Piston Gambar 3 Desain 3 unclassified

SIMULASI BATANG PENGHUBUNG PISTON DENGAN VARIASI MATERIAL Al Alloy DAN Ti Alloy MENGGUNAKAN METODE ELEMEN HINGGA

Putra

2020

G-Tech

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Motor bakar adalah motor yang dalam cara kerjanya membutuhkan pembakaran dengan merubah energi kimia menjadi energi mekanik. Pembakaran yang sering terjadi dalam ruang bakar dapat mengakibatkan panas dalam ruang bakar dimana pembakaran tersebut membutuhkan gerak bolak balik dari piston. Agar piston dapat berporasi normal maka, dibutuhkan komponen yang kuat untuk mendorong dan menopang piston tersebut. Komponen yang mendorong piston dalam dunia otomotif disebut dengan batang piston. Pemilihan material batang piston harus diperhatikan dengan ketelitian yang tinggi. Salah satu bahan penyusun material yang sering digunakan adalah Al Alloy dan Ti Alloy. Penelitian ini adalah untuk menguji dan menganalisis batang piston dengan metode elemen hingga. Analisis elemen hingga pada batang piston dilakukan dengan bantuan software ANSYS. Simulasi ANSYS dimaksudkan untuk menguji perbedaan total deformasi, tegangan normal, dan safety factor pada masing-masing material. Hasil analisis menunjukkan bahwa deformasi terbesar dialami pada batang piston dengan material Al Alloy dengan nilai 0,672 mm sedangkan pada material Ti Alloy deformasi yang dialami sebesar 0,496 mm.

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Bone-implant degradation and mechanical response of bone surrounding Mg-alloy implants

Cited by 26 publications

References 18 publications

The current trends of Mg alloys in biomedical applications—A review

The current trends of Mg alloys in biomedical applications—A review

3D nanoscale analysis of bone healing around degrading Mg implants studied by X-ray scattering tensor tomography

SIMULASI BATANG PENGHUBUNG PISTON DENGAN VARIASI MATERIAL Al Alloy DAN Ti Alloy MENGGUNAKAN METODE ELEMEN HINGGA

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