Bone Imaging in Advanced Gastric Cancer

Watanabe, Naoto; Haida, M; Mikuni, Ikuo; Shimizu, Masashi; Nakajima, Aiko; Seto, Hikaru

doi:10.1097/00003072-199806000-00014

Cited by 3 publications

(2 citation statements)

References 3 publications

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“…There are a few cases showing gastric uptake of tracer in advanced gastric cancer patients (10). However, the fact that the extent of tracer uptake is more diffuse and broader than that of gross calcifications seen on CT images makes our case unique.…”

Section: Discussionmentioning

confidence: 99%

Gastric Accumulation of Bone Seeking Agent in a Patient with Advanced Gastric Cancer

et al. 2007

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Soft tissue uptake of Tc-99m labeled bone seeking agents, such as Tc-99m 3,3-diphosphono-1,2-propanedicarboxylic acid (DPD), is commonly seen in clinical practice, even though bone scintigraphy is mainly used to detect bone disease. However, gastric uptake of bone agents in patients with gastric cancer is very rare. And it has been reported that calcified gastric adenocarcinoma appears in only about 5% of all gastric cancer. We report a rare case of bone scintigraphy, single photon emission computed tomography and computed tomography fusion images that demonstrated diffuse gastric uptake of Tc-99m DPD in a patient with advanced gastric cancer.

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Section: Discussionmentioning

confidence: 99%

Gastric Accumulation of Bone Seeking Agent in a Patient with Advanced Gastric Cancer

et al. 2007

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“…Anterior and posterior planar images from a subsequent whole body 99m-Tc-MDP bone scan were negative for suspicious osseous accumulation of radiotracer, but instead demonstrated a large discrete mass-like accumulation of extra-osseous 99m-Tc-MDP in the anterior left upper quadrant. Differential for this finding in an elderly patient included gastric lymphoma or cancer (1,2), metastatic melanoma (3,4) and heterotopic mesenteric ossification, such as from prior gastric bypass surgery (5,6). Gastric 99m-Tc-MDP uptake also has been observed in sarcoidosis (7) and diseases that cause hypercalcemia (8), including multiple myeloma (9), hyperparathyroidism (10) and vitamin D intoxication (11).…”

Section: Figure 1 -mentioning

confidence: 99%

Incidental Detection of Gastrointestinal Stromal Tumor by Tc-99m MDP Bone Scan

Shepherd

Idakoji²,

Pampaloni³

2012

Clinical Nuclear Medicine

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This case demonstrates extraosseous 99m-technetium methylene diphosphonate (Tc-99m MDP) accumulation from a gastrointestinal stromal tumor. A 75-year-old woman underwent a temporal bone CT for conductive hearing loss that showed sclerosis in the right occipital condyle. Follow-up Tc-99m MDP bone scan for osseous metastases instead showed a mass-like extraosseous accumulation of Tc-99m MDP in the anterior left upper quadrant. Differential diagnoses included gastric cancer, lymphoma, metastatic melanoma, systemic hypercalcemia, or heterotopic mesenteric ossification. Contrast CT showed a well-circumscribed mass arising from the stomach, and subsequent pathology confirmed gastrointestinal stromal tumor. These tumors rarely can contain osteoclast-like giant cells and should be considered for extraosseous Tc-99m MDP accumulation.

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Accumulation of Bone-Seeking Agent in a Patient With Mediastinal Seminoma

Kim

Jung²,

Park³

et al. 2010

Clinical Nuclear Medicine

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A 39-year-old man presented with substernal pain and shortness of breath. Bone scan revealed a large soft-tissue uptake in anterior chest. Subsequent computed tomography showed a large mass lesion with well demarcated margins in anterior mediastinum. Percutaneous core needle biopsy and histopathologic examination diagnosed the mediastinal seminoma. Bone scintigraphy could delineate a wide spectrum of nonosseous disorders. The recognition of extraskeletal uptake of bone-seeking agent can enhance the diagnostic value of bone scintigraphy.

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Bone Imaging in Advanced Gastric Cancer

Cited by 3 publications

References 3 publications

Gastric Accumulation of Bone Seeking Agent in a Patient with Advanced Gastric Cancer

Gastric Accumulation of Bone Seeking Agent in a Patient with Advanced Gastric Cancer

Incidental Detection of Gastrointestinal Stromal Tumor by Tc-99m MDP Bone Scan

Accumulation of Bone-Seeking Agent in a Patient With Mediastinal Seminoma

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