Bone growth to metal implants is regulated by their surface chemical properties

Hazan, Roni; Brener, R.; Oron, Uri

doi:10.1016/0142-9612(93)90172-x

Cited by 134 publications

(70 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Using CPI%, 4 different levels of toxicity have been identified, namely: "high toxicity" (CPI%=50), "medium toxicity" (CPI%<50% & >25%), "low toxicity" (CPI%<25%) and nontoxicity (CPI%=0). (Hazan, 1993).…”

Section: Wwwintechopencommentioning

confidence: 99%

Biological Reactions to Dental Implants

Ciocan¹,

Miculescu²,

Miculescu³

et al. 2011

Implant Dentistry - A Rapidly Evolving Practice

View full text Add to dashboard Cite

Section: Wwwintechopencommentioning

confidence: 99%

Biological Reactions to Dental Implants

Ciocan¹,

Miculescu²,

Miculescu³

et al. 2011

Implant Dentistry - A Rapidly Evolving Practice

View full text Add to dashboard Cite

“…15,16) Furthermore, TiO 2 coatings on Ti substrates have been used to improve the adhesion between an HAp coating and a Ti substrate. 17) From the viewpoint of bioactivity, we thought that the preparation of the TiO 2 / HAp composite coating would be a more promising approach than using individual coatings of HAp or TiO 2 .…”

Section: )mentioning

confidence: 99%

Formation of Titania/Hydroxyapatite Composite Films by Pulse Electrolysis

et al. 2007

View full text Add to dashboard Cite

The aim of this study was to examine the formation of titania (TiO 2 )/hydroxyapatite (HAp) composite films on a titanium substrate using anodic-cathodic pulse electrolysis. The TiO 2 /HAp composites were coated on commercially pure titanium plates (surface area: 1.0 cm 2 ) using pulse electrolysis in an autoclave in an aqueous solution that consisted of 0.3 mM Ca(H 2 PO 4 ) 2 and 0.7 mM CaCl 2 and pH ¼ 5:5 at 120 C. The pulse potentials were applied at þ8:7 V vs. Ag/AgCl sat. KCl as anodic potential and À9:3 V as cathodic. The total electrolysis time was 1800 s. We examined the effects of the electrolysis cycle (60 $ 600 s) and duty ratio on such properties of the coatings as the surface morphology, the amount of precipitated HAp, and the size of the HAp crystals. Prior to the pulse electrolysis, cathodic and anodic electrolysis experiments were also conducted. With pulse electrolysis, we could obtain TiO 2 /HAp composite films with fine HAp particles dispersed uniformly on a thin TiO 2 coating.

show abstract

“…Titanium being one of the most widely used metals for implants, since its introduction by Branemark et al [14], nanostructured tinanium oxide (titania) has been specifically used to improve bond adhesion and overall implant life time [15,16,17,18]. Several studies show that those titania materials which surface roughness better mimic the surface of natural bond, are more efficient increasing osteoblast function [5,7,17,18,19].…”

Section: Introductionmentioning

confidence: 99%

Ultrasonic tissue characterization for monitoring nanostructured TiO₂-induced bone growth

Rus¹,

Garcia-Martinez²

2007

Phys. Med. Biol.

View full text Add to dashboard Cite

Abstract. The use of bioactive nanostructured T iO 2 has recently been proposed for improving orthopaedic implant adhesion due to its improved biocompatibility with bone, since it induces: i) osteoblast function, ii) apatite nucleation and iii) protein adsorption. The present work focuses on a non-ionizing radiation emitting technique for quantifying in real-time the improvement in terms of mechanical properties of the surrounding bone due to the presence of the nanostructured T iO 2 prepared by controlled precipitation and acid aging. The mechanical strength is the ultimate goal of a bone implant, and is directly related to the elastic moduli. Ultrasonics are high frequency mechanical waves, and are therefore suited for characterizing elastic moduli. As opposed to echographic techniques, which are not correlated to elastic properties and are not able to penetrate bone, a low frequency ultrasonic transmission test is proposed, in which a P-wave is transmitted through the specimen and recorded. The problem is posed as an inverse problem, in which the unknown is a set of parameters that describe the mechanical constants of the sequence of layers. A finite element numerical model that depends on these parameters is used to predict the transformation of the waveform and compare to the measurement. The parameters that best describe the real tissue are obtained by minimizing the discrepancy between the real and numerically predicted waveform. A sensitivity study to the uncertainties of the model is performed for establishing the feasibility of using this technique to investigate the macroscopic effect on bone growth of nanostructured T iO 2 and its beneficial effect on implant adhesion.

show abstract

Bone growth to metal implants is regulated by their surface chemical properties

Cited by 134 publications

References 16 publications

Biological Reactions to Dental Implants

Biological Reactions to Dental Implants

Formation of Titania/Hydroxyapatite Composite Films by Pulse Electrolysis

Ultrasonic tissue characterization for monitoring nanostructured TiO₂-induced bone growth

Contact Info

Product

Resources

About

Bone growth to metal implants is regulated by their surface chemical properties

Cited by 134 publications

References 16 publications

Biological Reactions to Dental Implants

Biological Reactions to Dental Implants

Formation of Titania/Hydroxyapatite Composite Films by Pulse Electrolysis

Ultrasonic tissue characterization for monitoring nanostructured TiO2-induced bone growth

Contact Info

Product

Resources

About

Ultrasonic tissue characterization for monitoring nanostructured TiO₂-induced bone growth