Bone Grafting of Cryosurgically Treated Bone Defects: Experiments in Goats

Keijser, L. C. M.; Schreuder, H.W.B.; Boons, Harm W.; Keulers, Bram J.; Buma, P.; Huiskes, R.; Veth, R.P.H.

doi:10.1097/00003086-200203000-00032

Cited by 16 publications

(16 citation statements)

References 19 publications

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“…Most cavities were filled up with homologous bone chips after the curettage. Several studies have revealed that this leads to a complete consolidation and excellent functional results [18,19]. Thermal damage to the growth plate or articular cartilage was not seen in our group of patients.…”

Section: Discussionsupporting

confidence: 56%

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The cryosurgical treatment of chondroblastoma of bone: Long‐term oncologic and functional results

Geest

Noort

Schreuder

et al. 2007

Journal of Surgical Oncology

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Section: Discussionsupporting

confidence: 56%

“…Several adjuvant therapies have been described, such as phenol cauterization and bone cement [6][7][8][9] still the recurrence rate is reason for concern [6,9]. Therefore, cryosurgery was started as an adjuvant in our hospital in 1989 and is still the standard treatment of benign and low-grade malignant bone tumors [10,12,17,18].…”

Section: Introductionmentioning

confidence: 99%

The cryosurgical treatment of chondroblastoma of bone: Long‐term oncologic and functional results

Geest

Noort

Schreuder

et al. 2007

Journal of Surgical Oncology

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“…Nevertheless, six post-operative fractures took place after surgery with the prophylactic plating technique. From our studies in goats on the recovery of bone strength after cryosurgery we know that the strength of bone decreases by 30% 8 weeks after surgery and it takes at least 26 weeks for the bone to regain its normal strength [23].…”

Section: Discussionmentioning

confidence: 99%

“…We observed that the regaining of the mechanical strength of bone after cryosurgery in goats reflects the same time period as in human bone [24]. Revascularization of biological grafts is reduced due to the necrosis following cryosurgery and consequently supplies less stability in the first post-operative months [23,25]. Intra-operative care can make a difference in complication incidence by adjusting the outline of the cortical window or the method of osteosynthesis [23].…”

Section: Discussionmentioning

confidence: 99%

“…Revascularization of biological grafts is reduced due to the necrosis following cryosurgery and consequently supplies less stability in the first post-operative months [23,25]. Intra-operative care can make a difference in complication incidence by adjusting the outline of the cortical window or the method of osteosynthesis [23]. The decision to use prophylactic osteosynthesis depends on the site and size of the lesion.…”

Section: Discussionmentioning

confidence: 99%

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Oncological and functional results of cryosurgical therapy of enchondromas and chondrosarcomas grade 1

Geest

Valk

Rooy

et al. 2008

Journal of Surgical Oncology

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Rigid‐rod polybenzoxazoles containing perylene bisimide: Synthesis, structures and photophysical properties

Liu

Zhuang

et al. 2009

J of Applied Polymer Sci

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There is movement to expand newborn screening (NBS) to include conditions that challenge the traditional public health screening criteria. Little is known about the attitudes of genetic counselors towards expanding NBS and offering predictive genetic tests to children. For our study genetic counselors completed an internet survey posted on the National Society of Genetic Counselors Listserv regarding five conditions: cystic fibrosis (CF), Duchenne muscular dystrophy (DMD), glucose‐6‐phosphate dehydrogenase deficiency (G6PD), fragile X (FraX), and type 1 diabetes (T1D). The survey addressed attitudes towards: (1) testing high‐risk infants; (2) mandatory NBS; (3) population screening beyond the newborn period; and (4) testing one's own child. Two hundred sixty‐seven usable surveys were received. Over two‐thirds of respondents supported testing high‐risk infants for all conditions except T1D (22%). CF was the only condition for which there was majority support for both mandatory NBS (56%) and later population screening (60%). For all other conditions, later population screening was preferred over NBS (P ≤ 0.01). Genetic counselors were most likely to test their own child for CF (46%) and least likely to test their own child for T1D (6%). For each condition, genetic counselors were more likely to support NBS if they chose to screen their own newborn (P < 0.001). Attitudes towards NBS were not influenced by year of graduation or professional experience. We can conclude that genetic counselors are supportive of targeted testing of high‐risk infants. They prefer voluntary population screening with consent to mandatory NBS for conditions that challenge Wilson and Jungner criteria. Their support for NBS correlates with their interest in testing their own children and not with professional experience. © 2006 Wiley‐Liss, Inc.

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Bone Grafting of Cryosurgically Treated Bone Defects: Experiments in Goats

Cited by 16 publications

References 19 publications

The cryosurgical treatment of chondroblastoma of bone: Long‐term oncologic and functional results

The cryosurgical treatment of chondroblastoma of bone: Long‐term oncologic and functional results

Oncological and functional results of cryosurgical therapy of enchondromas and chondrosarcomas grade 1

Rigid‐rod polybenzoxazoles containing perylene bisimide: Synthesis, structures and photophysical properties

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