Bone Graft Materials for Alveolar Bone Defects in Orthodontic Tooth Movement

Lu, Jiajia; Wang, Zishuo; Zhang, Hongyan; Xu, Wenhua; Zhang, Chengfei; Yang, Yanjie; Zheng, Xianyu; Xu, Jianguang

doi:10.1089/ten.teb.2020.0212

Cited by 25 publications

(39 citation statements)

References 85 publications

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“…The differences can be attributed to the patient's age, variation in the individual bone remodelling rate, and different graft materials. 14,15 An autogenous bone graft, although associated with increased patient morbidity, possessed the ability to initiate osteogenesis and prompt bone remodelling, which might explain the space management efficiency in Case 2 after grafting. 15 In Case 1, the mechanics A recent animal study suggested that the optimal timing for applying orthodontic force is 4 weeks after a xenograft and a bio-resorbable membrane have been placed, 16 whereas immediate orthodontic traction has been suggested at the xenograft site.…”

Section: Discussionmentioning

confidence: 99%

Edentulous ridge space closure after bone augmentation using different graft materials: A report of two cases

Lin

Sun

Chou

et al. 2022

Australasian Orthodontic Journal

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Post-extraction alveolar ridge resorption is a common sequela when missing mandibular molar spaces are not managed in a timely fashion. The situation becomes more complicated in patients who seek orthodontic treatment if closure of the edentulous space is the major objective in order to avoid prosthetic rehabilitation. In the present article, two cases are reported, in which different bone augmentation graft materials were used and treatment duration and post-orthodontic alveolar ridge characteristics were compared. A regional acceleratory phenomenon after the grafting procedure facilitated uneventful orthodontic space closure. The status of the investing alveolar bone was compared using post-treatment cone-beam computed tomography. Both autogenous bone graft and allograft ridge augmentation procedures aided in successful molar protraction through the resorbed mandibular alveolar ridge, as well as preventing periodontal attachment loss.

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Section: Discussionmentioning

confidence: 99%

Edentulous ridge space closure after bone augmentation using different graft materials: A report of two cases

Lin

Sun

Chou

et al. 2022

Australasian Orthodontic Journal

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“…Based on where bone grafts are sourced, they may be categorized as autografts, allografts, xenografts, or synthetics. Autografts prevail amongst these categories in the maxillofacial region and are the current gold standard as they [1] consist of an abundance of spongy bone that is close to the alveolar bone structure, [2] display osteoconductive and osteoinductive potential ( Boyne and Sands, 1972 ; Enemark et al, 1987 ; Ozaki and Buchman, 1998 ), and [3] promote periodontal regeneration ( Ivanovic et al, 2014 ) without significantly unfavorable sequelae when teeth are orthodontically moved into grafted areas ( Lu et al, 2021 ). However, the drawbacks of autografts are substantial, including but not limited to inadequate availability, expensive cost, mismatched size, and inevitable additional surgery for autograft harvest ( Sharif et al, 2016 ).…”

Section: Introductionmentioning

confidence: 99%

“…Allografts, such as decalcified freeze-dried bone allogeneic grafts (DFDBA) and freeze-dried bone allogeneic grafts (FDBA), are orthodontic-friendly ( Lu et al, 2021 ); however, their osteoinductive potency is not conclusive ( Schwartz et al, 1998 ). Xenografts, such as Bio-Oss® and Gen-Tech®, are the most common alveolar grafting materials for clinical use.…”

Section: Introductionmentioning

confidence: 99%

“…Xenografts, such as Bio-Oss® and Gen-Tech®, are the most common alveolar grafting materials for clinical use. They are successful when used for alveolar bone augmentation ( da Silva et al, 2020 ), but can severely impair orthodontic treatment and cause substantial root resorption when teeth are moved into the grafted region ( Lu et al, 2021 ). Although synthetic bone grafts, such as NanoBone® and BoneCeramic®, also promote bone augmentation, major adverse effects (namely root resorption and gingival invagination) make them an unfavorable choice for pre-orthodontic alveolar bone grafting ( Lu et al, 2021 ).…”

Section: Introductionmentioning

confidence: 99%

“…They are successful when used for alveolar bone augmentation ( da Silva et al, 2020 ), but can severely impair orthodontic treatment and cause substantial root resorption when teeth are moved into the grafted region ( Lu et al, 2021 ). Although synthetic bone grafts, such as NanoBone® and BoneCeramic®, also promote bone augmentation, major adverse effects (namely root resorption and gingival invagination) make them an unfavorable choice for pre-orthodontic alveolar bone grafting ( Lu et al, 2021 ). Therefore, there is an emerging need for new grafting materials to be not only osteoinductive and osteoconductive but also supportive of highly active bone metabolism during orthodontic tooth movement without adverse effects.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Impact of Frontier Development of Alveolar Bone Grafting on Orthodontic Tooth Movement

Miao

Chang

Tanna

et al. 2022

Front. Bioeng. Biotechnol.

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Sufficient alveolar bone is a safeguard for achieving desired outcomes in orthodontic treatment. Moving a tooth into an alveolar bony defect may result in a periodontal defect or worse–tooth loss. Therefore, when facing a pathologic situation such as periodontal bone loss, alveolar clefts, long-term tooth loss, trauma, and thin phenotype, bone grafting is often necessary to augment bone for orthodontic treatment purposes. Currently, diverse bone grafts are used in clinical practice, but no single grafting material shows absolutely superior results over the others. All available materials demonstrate pros and cons, most notably donor morbidity and adverse effects on orthodontic treatment. Here, we review newly developed graft materials that are still in the pre-clinical stage, as well as new combinations of existing materials, by highlighting their effects on alveolar bone regeneration and orthodontic tooth movement. In addition, novel manufacturing techniques, such as bioprinting, will be discussed. This mini-review article will provide state-of-the-art information to assist clinicians in selecting grafting material(s) that enhance alveolar bone augmentation while avoiding unfavorable side effects during orthodontic treatment.

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A Mechanically Reinforced Super Bone Glue Makes a Leap in Hard Tissue Strong Adhesion and Augmented Bone Regeneration

Wang

et al. 2023

Advanced Science

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Existing bone tissue engineering strategies aim to achieve minimize surgical trauma, stabilize the injured area, and establish a dynamic osteogenic microenvironment. The cutting-edge bone glue developed in this study satisfies these criteria. Inspired by the excellent adhesive properties of mussels, herein, a super osteogenic glue (L-DPZ) that integrates poly(vinyl alcohol), L-dopa amino acid, and zeolitic imidazolate framework-8 characterized by catechol-metal coordination is used to successfully adhere to hard tissue with a maximum adhesive strength of 10 MPa, which is much higher than those of commercial and previously reported bone glues. The stable hard tissue adhesion also enables it to adhere strongly to luxated or broken teeth, Bio-Oss (a typical bone graft material), and splice fragments from comminuted fractures of the rabbit femur. Then, it is testified that the L-DPZ hydrogels exhibit satisfactory biocompatibility, stable degradability, and osteogenic ability in vitro. Moreover, the ability to anchor Bio-Oss and sustained osteogenesis of L-DPZ result in satisfactory healing in calvarial bone defect models in rabbits, as observed by increased bone thickness and the ingrowth of new bone tissue. These results are expected to demonstrate solutions to clinical dilemmas such as comminuted bone fracture fixation, bone defect reconstruction, and teeth dislocation replantation.

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Bone Graft Materials for Alveolar Bone Defects in Orthodontic Tooth Movement

Cited by 25 publications

References 85 publications

Edentulous ridge space closure after bone augmentation using different graft materials: A report of two cases

Edentulous ridge space closure after bone augmentation using different graft materials: A report of two cases

Impact of Frontier Development of Alveolar Bone Grafting on Orthodontic Tooth Movement

A Mechanically Reinforced Super Bone Glue Makes a Leap in Hard Tissue Strong Adhesion and Augmented Bone Regeneration

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