Bone Graft and Substitutes Associated with Titanium Dome for Vertical Bone Formation in Osseointegrated Implants: Histomorphometric Analysis in Dogs

Zendron, Mario Vinicius; Cardoso, Matheus Völz; Veronesi, Giovana Fuzeto; Resende, Daniel Romeu Benchimol de; Damante, Carla Andreotti; Sant’Ana, Adriana Campos Passanezi; Greghi, Sebastião Luis Aguiar; Zangrando, Mariana Schützer Ragghianti

doi:10.11607/jomi.5762

Cited by 3 publications

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“…Because of this, the application of the guided bone regeneration techniques associated with the use of bone grafts in patients with inadequate bone volume for the installation of implants has been widely encouraged (2). Among the types of bone substitutes, the autografts have been considered the standard due to the biological superiority of this type of bone graft (2,3). However, the risk of morbidity at the donor site and the limitation of quantity disponible presented in some cases led to the use of alternative bone substitutes for this purpose (4,5).…”

Section: Introductionmentioning

confidence: 99%

Effect of different thresholds on the accuracy of linear and volumetric analysis of native- and grafted-bone

et al. 2022

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The study aimed to evaluate the accuracy of Micro-CT in linear and volumetric measurements in native (NB) and grafted bone (GB) areas. A total of 111 biopsies of maxillary sinuses grafted with deproteinized bovine bone (DBB) in humans were evaluated. The linear measurements were performed to measure the length of the NB and GB. Furthermore, the amount of mineralized tissues at the NB and GB was performed. In the histomorphometry analysis the percentage of mineralized tissues at the NB and GB was obtained in two histological sections while the mineralized tissues were measure in the micro-CT varying the thresholds of the grayscale varying from 90-250 to 90-150 with 10 levels of variation between each one was applied. Then these data were correlated in order to check the higher r level between the histomorphometry and micro-CT thresholds intervals. The linear length of the NB was 2.44±0.91mm and 2.48±1.50mm, respectively, for micro-CT and histomorphometry (r =0.57), while the linear length of the GB was 3.63±1.66mm and 3.13±1.45mm, respectively, for micro-CT and histomorphometry (r =0.74) Histomorphometry showed 45.91±11.69% of bone in NB, and 49.57±5.59% of bone and biomaterial in the GB. The total volume of mineralized tissues that were closest to the histometric analysis were 43.75±15.39% in the NB (Threshold:90-240; r = 0.50) and 51.68±8.42% in the GB (Threshold:90-180; r =-0.028). The micro-CT analysis showed good accuracy in the linear analysis in both portions of the biopsies but for volumetric analysis just in NB.

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Section: Introductionmentioning

confidence: 99%

Effect of different thresholds on the accuracy of linear and volumetric analysis of native- and grafted-bone

et al. 2022

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“…These biomaterials have shown to be effective in increasing bone availability associated with maxillary sinus floor augmentation 4 , in alveolar ridge preservation following tooth extraction 6 and in lateral ridge augmentation 7 . However, in spite of these benefits, the use of strictly osteoconductive biomaterials has shown to reduce the formation of bone tissue in comparison to areas grafted with autogenous bone 8 , to reduce bone formation in noncritical size defects compared to those that were filled with clots 9 and to have worse implant osseointegration compared to implants placed in native bone 10 .…”

Section: ■ Introductionmentioning

confidence: 99%

Local effect of simvastatin combined with different osteoconductive biomaterials and collagen sponge on new bone formation in critical defects in rat calvaria

et al. 2020

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To evaluate the local effect of simvastatin (SVT) combined with deproteinized bovine bone (DBB) with hydroxyapatite/β-tricalcium phosphate biphasic ceramics (HA/TCP) and with collagen sponge (CS) on bone repair in critical size defects (CSDs) in rat calvaria. Methods: Forty-two 5-mm diameter CSDs were made bilaterally in the calvaria of 18 rats. The animals were allocated according to the type of biomaterial and associations used to fill the CSD. After 8 weeks, the animals were euthanized, and their calvaria were evaluated for repaired tissue composition using histologic and histometric analyses. Results: In the histometric analysis, the use of SVT showed to increase bone formation in the CSDs when combined with all the bone substitutes tested in this study (p<0.05). Greater bone formation was observed in the groups with SVT compared to the groups without SVT. Conclusions: The use of SVT without the need for a vehicle and combined with a commercially available biomaterial may be a cheaper way to potentiate the formation of bone tissue without the need to produce new biomaterials. Therefore, SVT combined with DBB induced significantly greater new bone formation than did the other treatments.

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Biogran Grafting in Rat Tibia Defects - A Model of High Bone Metabolism Site

Ferreira,

Lehman,

Diniz

et al. 2024

Braz. arch. biol. technol.

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Bone Graft and Substitutes Associated with Titanium Dome for Vertical Bone Formation in Osseointegrated Implants: Histomorphometric Analysis in Dogs

Cited by 3 publications

References 0 publications

Effect of different thresholds on the accuracy of linear and volumetric analysis of native- and grafted-bone

Effect of different thresholds on the accuracy of linear and volumetric analysis of native- and grafted-bone

Local effect of simvastatin combined with different osteoconductive biomaterials and collagen sponge on new bone formation in critical defects in rat calvaria

Biogran Grafting in Rat Tibia Defects - A Model of High Bone Metabolism Site

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