Bone disease in a dog similar to infantile cortical hyperostosis (Caffey's disease)

A Case of Congenital Hyperostosis in a Newborn Piglet

“…Actually, the case described by Baker and Lewis did not fit the genetic etiology [3]. Although the pathogenesis in the present case is not known, the periosteal reaction is consistent with that in previous cases, and edema caused by a local circulatory disturbance is suggesting the possibility of localized hypertensive changes as a cause.…”

“…Diseases similar to congenital hyperostosis in newborn pigs have been reported in human [4] and other animal species including monkeys [10], dogs [2,3], foals [12] and chickens [5]. Among them, most intensely investigated one is infantile cortical hyperostosis in human, which is also known as Caffey's disease [4].…”

CALVARIAL hYPEROSTOSIS SYNDROME IN TWO bULLMASTIFFS

“…Given the similar radiographic and clinical findings with calvarial hyperostosis syndrome, it is possible that calvarial hyperostosis syndrome is simply a variant of craniomandibular osteopathy. There is, however, confusion regarding the pathological findings, with craniomandibular osteopathy reported to be both similar to and different from infantile cortical hyperostosis 1,2,5–7 . Infantile cortical hyperostosis and calvarial hyperostosis syndrome are reported as being predominately inflammatory subperiosteal or periosteal diseases 1,2,7 .…”

“…Infantile cortical hyperostosis and calvarial hyperostosis syndrome are reported as being predominately inflammatory subperiosteal or periosteal diseases 1,2,7 . Craniomandibular osteopathy by comparison is reported to differ from infantile cortical hyperostosis by predominately resulting in irregular deposition and resorption of bone resulting in a mosaic of poorly mineralized tissue 6 . The inflammatory component of craniomandibular osteopathy is variable.…”

“…1,2,7 Craniomandibular osteopathy by comparison is reported to differ from infantile cortical hyperostosis by predominately resulting in irregular deposition and resorption of bone resulting in a mosaic of poorly mineralized tissue. 6 The inflammatory component of craniomandibular osteopathy is variable. The confusion may simply be because of the fact that bone has a limited number of responses to injury and different diseases result in similar radiographic changes.…”