2012
DOI: 10.1007/s10803-012-1709-3
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Bone Density in Peripubertal Boys with Autism Spectrum Disorders

Abstract: We determined whether bone mineral density (BMD) is lower in boys with autism spectrum disorders (ASD) than controls, and also assessed variables that may affect BMD in ASD. BMD was measured using dual energy X-ray absorptiometry (DXA) in 18 boys with ASD and 19 controls 8–14 years old. Boys with ASD had lower BMD Z-scores at the spine, hip and femoral neck, and differences at the hip and femoral neck persisted after controlling for maturity and BMI. Vitamin D intake from food and in serum were lower in ASD su… Show more

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Cited by 79 publications
(92 citation statements)
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References 33 publications
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“…In our patient, treatment was completed in 13 months, which was markedly shorter than usual extraction treatments (13,14). It was previously reported that boys with ASD have a lower bone mineral density than controls (15). The shortened treatment duration may be related to decreased bone mineral density levels, resulting in faster tooth movement.…”
Section: Discussionmentioning
confidence: 71%
“…In our patient, treatment was completed in 13 months, which was markedly shorter than usual extraction treatments (13,14). It was previously reported that boys with ASD have a lower bone mineral density than controls (15). The shortened treatment duration may be related to decreased bone mineral density levels, resulting in faster tooth movement.…”
Section: Discussionmentioning
confidence: 71%
“…The ASD cases have reportedly abnormal bone density thus increased risk for fractures 4 . Young and adult cases of ASD have been found to have an increased odds ratio of fracture around hip, forearm and spine 3,5 . Our case reported trivial fall resulting in a closed short oblique fracture pattern and that suggests subnormal bone strength 6 .…”
Section: Discussionmentioning
confidence: 99%
“…The bone density in patients affected with ASD has been found to be subnormal and decreased exercise and low vitamin D through diet or sun exposure might be additional causes for it 2 . The decreased bone mass may cause fractures but the literature regarding fracture in these cases is limited 3 . The treatment part is compounded with problems of social and behavioral disorders inherent to ASD.…”
Section: Introductionmentioning
confidence: 99%
“…35,36 . Another study from Brazil reported lower level of Vitamin D in children with ASD than controls and a mean serum value of 26.5 ng/mL 28,37 . In a study conducted in the Faroe Islands as part of a population based study, lower Vitamin D levels (mean : 9.9 ng/mL) were reported in 40 individuals (aged 15-24 years) with ASD, as compared to their normally developing siblings, parents, and age-and gender-matched healthy controls 38 .…”
Section: Table 3: Spearman Correlation Between Serum and Dietary Vitamentioning
confidence: 94%
“…Mann-Whitney test,* significance difference ** Serum Creatinine normal levels (male:0.9-1.5 mg/dl, female:0.7-1.4 mg/dl) Herndon found that both autistic and control groups had comparable inadequacy of Vitamin D in their diet which was similar to our findings. However, Neumeyer reported that autistic children was much lower than control group with both less than daily recommended allowance 28 . Furthermore, there were many studies reported that even healthy children did not reach the recommended Vitamin D intake in their diets as in Europe, Saudi Arabia, Beirut and Israel [29][30][31][32] .…”
Section: Table 3: Spearman Correlation Between Serum and Dietary Vitamentioning
confidence: 95%