Bone densitometry by radiofrequency echographic multi-spectrometry (REMS) in the diagnosis of osteoporosis

Iwaszkiewicz, Cezary; Leszczyński, P

doi:10.5603/fr.2019.0011

Cited by 3 publications

(3 citation statements)

References 21 publications

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“…The early diagnosis of acromegaly and investigations for new markers as well as for new diagnostic methods for assessing the risk of osteoporotic fractures are very important to improve care of acromegaly patients. REMS technology is one of the promising new methods proposed in the screening of osteoporosis [21,28]. In our study we analysed results of densitometry performed with novel REMS method and traditional DXA in acromegaly patients.…”

Section: Discussionmentioning

confidence: 99%

Bone densitometry by radiofrequency echographic multi-spectrometry (REMS) in acromegaly patients

Rolla

Halupczok-Żyła

Jawiarczyk-Przybyłowska

et al. 2020

Endokrynologia Polska

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Introduction: Radiofrequency echographic multi-spectrometry (REMS) is a recently introduced non-ionising technology employed in the evaluation of osteoporosis. The aim of our study was to compare bone mineral density (BMD) in acromegaly patients and healthy controls by performing novel REMS densitometry. The second objective was to analyse the correlation between results of REMS and classical dual-energy X-ray absorptiometry (DXA) in acromegaly patients. 2 Material and methods: We enrolled 33 patients with acromegaly (AG) and 24 controls (CG). The acromegaly patients were divided into two subgroups: well-controlled acromegaly (WCA) and surgery-cured acromegaly (SCA). REMS was performed in all participants, while DXA was performed only in the acromegaly group. IGF-I and GH levels were measured in acromegaly patients. Results: Bone mineral density of the lumbar spine (LS) and the femoral neck (FN) obtained from REMS did not reveal significant differences between AG, CG, WCA, and SCA. Similarly, there were no significant differences in BMD measured by DXA at the LS and at the FN between WCA and SCA. Significant positive correlations between IGF-I concentrations and BMD obtained from both REMS and DXA were detected in the AG and WCA. In the AG and WCA, there were positive correlations between T-scores and LS BMD obtained from both methods. Conclusions: Radiofrequency echographic multi-spectrometry is a potential method in assessment of bone status in acromegaly. Further studies with participation of active disease patients are needed.

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Section: Discussionmentioning

confidence: 99%

Bone densitometry by radiofrequency echographic multi-spectrometry (REMS) in acromegaly patients

Rolla

Halupczok-Żyła

Jawiarczyk-Przybyłowska

et al. 2020

Endokrynologia Polska

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“…The clinical risk factors in the FRAX model are on one hand easily accessible and on the other hand highly validated from an evidence-based assessment [22]. Furthermore, FRAX tool has been incorporated into the software of some DXA scanners [23,24]. In the current study, the opportunity to assess the 10-year fracture risk with REMS technology, which has integrated Fracture Risk Assessment Tool (FRAX) [25], motivated us to describe the patients' characteristics in the different FRAX risk groups with this novel method.…”

Section: Discussionmentioning

confidence: 99%

Assessment of Fracture Risk through Radiofrequency Echographic Multi Spectrometry (REMS) based Bone Mineral Density

Kirilova¹

2019

OROAJ

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Introduction: Fracture Risk Assessment Tool (FRAX) was developed by the World Health Organization (WHO) to be applicable to both postmenopausal women and men aged 40 to 90 years. The current National Osteoporosis Foundation Guide recommends treating patients with FRAX 10-year risk scores of > or = 3% for hip fracture or > or = 20% for major osteoporotic fracture, to reduce their fracture risk.Methods: 189 postmenopausal women with mean age 60 years ± 9 standard deviations (SD), (range 40-86) were included in the study. Women were divided in 2 fracture risk groups: 1st -with FRAX score for major osteoporotic fracture below 20% and for hip fracture below 3%, and 2nd -with FRAX score for major osteoporotic fracture ≥ 20% and for hip fractures ≥3%. Descriptive statistical analysis was used to describe the patients' characteristics in both groups. Independent sample t-test was used to assess the significant association between the quantitative variables and chi-square test -for the qualitative variables.Results: 77.8% of the women (147/189) had FRAX score for major osteoporotic fracture below 20% and 22.2% (42/189) with FRAX score ≥20%. 62.4% (118/189) of the women had FRAX score for hip fracture below 3% and 37.6% (71/189) had FRAX score ≥3%. Women with FRAX score for major osteoporotic fracture ≥20% and FRAX score for hip fracture ≥3% were significantly older (p=0.000), had significantly lower weight (p=0.000), height (p=0.000) and femoral neck BMD (p=0.000) compared to those with FRAX score for major osteoporotic fracture below 20% and FRAX score for hip fracture below 3%. Conclusion:Postmenopausal women at older ages, with low femoral neck BMD, low weight and height, who had previous fractures, have diagnosis of Rheumatoid arthritis (RA) and use corticosteroids are at the highest risk of FRAX for major osteoporotic fractures ≥20% and for hip fractures ≥3%.

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“…The measured data are synthesized into a patient-specific spectrum that is compared to reference spectral models matched by gender, age, site, and BMI in a database. The spectral modifications introduced by the physical properties of bone structure that back-diffuse the ultrasound signals are identified via a comparison procedure to determine an estimate of the BMD and the consequent diagnostic classification of healthy, osteopenic, or osteoporotic [9,10].…”

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confidence: 99%

Radiofrequency Echographic Multi Spectrometry (R.E.M.S.): New Frontiers for Ultrasound Use in the Assessment of Bone Status—A Current Picture

et al. 2023

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Osteoporosis is a frequently occurring skeletal disease, and osteoporosis-related fractures represent a significant burden for healthcare systems. Dual-Energy X-ray Absorptiometry (DXA) is the most commonly used method for assessing bone mineral density (BMD). Today, particular attention is being directed towards new technologies, especially those that do not use radiation, for the early diagnosis of altered bone status. Radiofrequency Echographic Multi Spectrometry (REMS) is a non-ionizing technology that evaluates the bone status at axial skeletal sites by analyzing raw ultrasound signals. In this review, we evaluated the data on the REMS technique present in the literature. The literature data confirmed diagnostic concordance between BMD values obtained using DXA and REMS. Furthermore, REMS has adequate precision and repeatability characteristics, is able to predict the risk of fragility fractures, and may be able to overcome some of the limitations of DXA. In conclusion, REMS could become the method of choice for the assessment of bone status in children, in women of childbearing age or who are pregnant, and in several secondary osteoporosis conditions due to its good precision and replicability, its transportability, and the absence of ionizing radiation. Finally, REMS may allow qualitative and not just quantitative assessments of bone status.

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Bone densitometry by radiofrequency echographic multi-spectrometry (REMS) in the diagnosis of osteoporosis

Cited by 3 publications

References 21 publications

Bone densitometry by radiofrequency echographic multi-spectrometry (REMS) in acromegaly patients

Bone densitometry by radiofrequency echographic multi-spectrometry (REMS) in acromegaly patients

Assessment of Fracture Risk through Radiofrequency Echographic Multi Spectrometry (REMS) based Bone Mineral Density

Radiofrequency Echographic Multi Spectrometry (R.E.M.S.): New Frontiers for Ultrasound Use in the Assessment of Bone Status—A Current Picture

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