Bone and joint bacterial infections in patients with rheumatoid arthritis

Masala, Ignazio Francesco; Marino, Francesca; Sarzi‐Puttini, Piercarlo; Atzeni, Fabiola

doi:10.1016/b978-0-444-64217-2.00008-7

Cited by 2 publications

(2 citation statements)

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“…Common symptoms of systemic inflammation include fever, general weakness, and fatigue. 9 The most well-known antibodies in RA are rheumatoid factor (RF) and anti-citrulline protein (ACPA) antibodies, which are present long before the onset of the disease. 10 Vitamin D, as one of the most important vitamins needed in the body, plays an important role in bone formation, including the physiological system, including the immune system.…”

Section: Introductionmentioning

confidence: 99%

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Relationship Between Serum Vitamin D Level and Disease Severity in Rheumatoid Arthritis

Soltani Bajestani,

Khajavian,

Salarbashi

et al. 2023

Clin Med�Insights�Arthritis�Musculoskelet Disord

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Background and Objective: Rheumatoid arthritis is an autoimmune disease that causes joint pain and reduces daily activities. The aim of this study was to evaluate the serum of vitamin D and its relationship with the severity of the disease in patients with rheumatoid arthritis referred to Allameh Hehlool hospital in Gonabad. Design and Methods: This cross-sectional-analytical study was performed on 92 patients referred to the rheumatology clinic of Allameh Behlool Gonabad Hospital in 2021. After obtaining the permission of the ethics committee, the samples were selected based on the desired criteria. Serum vitamin D levels in patients were measured, and data were collected using a patient information checklist and DAS28-CRP activity questionnaire. Data were analyzed using SPSS software version 16 and using statistically appropriate tests at a significance level less than 5%. Results: The mean age of the patients was 53.05 ± 12.33 years and most of them (58.7%) were women. Serum vitamin D level was sufficient in 65.2% of patients and the severity of the disease was in the remission in 48.9% of them. The results of chi-square test showed a significant relationship between serum vitamin D levels and disease severity in patients ( P < .001). Conclusions: Serum vitamin D levels were inversely related to disease severity and in most patients with severe disease severity, serum vitamin D levels were inadequate. vitamin D supplementation is recommended in patients with rheumatoid arthritis.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%