Bone and Cartilage – its Structure and Physical Properties

Wojnar, R.

doi:10.1002/9783527632732.ch1

Cited by 9 publications

(8 citation statements)

References 186 publications

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“…During intramembranous bone formation, the connective tissue membrane of undifferentiated mesenchymal cells changes into bone and matrix bone cells [10]. In the craniofacial cartilage bones, intramembranous ossification originates from nerve crest cells.…”

Section: Intramembranous Bone Formationmentioning

confidence: 99%

“…Here, the osteoblasts form a periosteal collar of compact bone around the cartilage of the diaphysis. By the second or third month of fetal life, bone cell development and ossification ramps up and creates the primary ossification center, a region deep in the periosteal collar where ossification begins [4,10].…”

mentioning

confidence: 99%

“…By the time the fetal skeleton is fully formed, cartilage only remains at the joint surface as articular cartilage and between the diaphysis and epiphysis as the epiphyseal plate, the latter of which is responsible for the longitudinal growth of bones. After birth, this same sequence of events (matrix mineralization, death of chondrocytes, invasion of blood vessels from the periosteum, and seeding with osteogenic cells that become osteoblasts) occur in the epiphyseal regions, and each of these centers of activity is referred to as a secondary ossification center [4, 8,10].…”

mentioning

confidence: 99%

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Bone Development and Growth

Setiawati¹,

Rahardjo²

2019

Osteogenesis and Bone Regeneration

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The process of bone formation is called osteogenesis or ossification. After progenitor cells form osteoblastic lines, they proceed with three stages of development of cell differentiation, called proliferation, maturation of matrix, and mineralization. Based on its embryological origin, there are two types of ossification, called intramembranous ossification that occurs in mesenchymal cells that differentiate into osteoblast in the ossification center directly without prior cartilage formation and endochondral ossification in which bone tissue mineralization is formed through cartilage formation first. In intramembranous ossification, bone development occurs directly. In this process, mesenchymal cells proliferate into areas that have high vascularization in embryonic connective tissue in the formation of cell condensation or primary ossification centers. This cell will synthesize bone matrix in the periphery and the mesenchymal cells continue to differentiate into osteoblasts. After that, the bone will be reshaped and replaced by mature lamellar bone. Endochondral ossification will form the center of primary ossification, and the cartilage extends by proliferation of chondrocytes and deposition of cartilage matrix. After this formation, chondrocytes in the central region of the cartilage start to proceed with maturation into hypertrophic chondrocytes. After the primary ossification center is formed, the marrow cavity begins to expand toward the epiphysis. Then the subsequent stages of endochondral ossification will take place in several zones of the bone.

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Section: Intramembranous Bone Formationmentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

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Bone Development and Growth

Setiawati¹,

Rahardjo²

2019

Osteogenesis and Bone Regeneration

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“…Bone is a complex tissue which integrates two basic components, organic (matrix) and inorganic (mineral) material [1]. Its high strength and fracture toughness is achieved by a unique architecture of organic and inorganic phases [2][3][4].…”

Section: Issn: 2348-9812mentioning

confidence: 99%

Structural, Elemental and Molecular Characterization of Normal And Osteoarthritic Human Articular Cartilage

Çayır¹,

Akaltun²,

Memişoğlu³

et al. 2017

JOURNAL OF MATERIALS SCIENCE AND NANOTECHNOLOGY

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“…São formados por duas partes distintas, sendo uma inorgânica, correspondendo de 70% a 60% do peso do osso, e outra orgânica, correspondendo a 30% a 20% do peso (Rodrigues, 2012;Polo-Corrales et al, 2014). Cerca de 2% do peso do osso são referentes a componentes celulares, responsáveis pela regeneração e nutrição do osso e em torno de 10% de seu peso total é água (Wojnar et al, 2010).…”

Section: Ossounclassified

Desenvolvimento de matrizes de colágeno/nanohidroxiapatita contendo extratos vegetais para regeneração óssea

Garcia¹

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Bone and Cartilage – its Structure and Physical Properties

Cited by 9 publications

References 186 publications

Bone Development and Growth

Bone Development and Growth

Structural, Elemental and Molecular Characterization of Normal And Osteoarthritic Human Articular Cartilage

Desenvolvimento de matrizes de colágeno/nanohidroxiapatita contendo extratos vegetais para regeneração óssea

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