Bonding and structure trends of thiosemicarbazone derivatives of metals—An overview

Copper(II) complexes derived from di-2-pyridyl ketone-N4-phenyl-3-semicarbazone: Synthesis and spectral studies

“…Electronic spectra were recorded on a Cary 5000, version 1.09 UV-VIS-NIR spectrophotometer in the 200-900 nm range using solutions in DMSO. Magnetic susceptibility measurements were carried out on a Vibrating Sample Magnetometer using Hg[Co(SCN) 4 ] as a calibrant. The EPR spectra of polycrystalline samples at 298 K and solution at 77 K were recorded on a Varian E-112 X-band EPR spectrometer with 100-kHz field modulation and g factors were quoted relative to the standard marker TCNE (g = 2.00277).…”

“…The biological activity is due to the ability to form chelates with transition metal ions bonding through oxygen and azomethine nitrogen atoms. Compared with thiosemicarbazone analogues, there are considerably less reports on the synthesis, structures and spectroscopic characterization of semicarbazones and their metal complexes [4]. Semicarbazones derived from di-2-pyridyl ketone have a small negative charge resides on the nitrogen atom of the pyridine ring which enhances its biological activity [5].…”

Crystal structure of bis(N′-((1H-pyrrol-2-yl)methylene)-1-methylthio-methanethiohydrazido-κ2 S,N)nickel(II), C14H16N6NiS4

“…Our previous work shows that copper(II) and nickel(II) complexes of TSCs bearing pyrrole unit have potential antitumor activity [5]. However, as their structurally analogous, methylthiomethanethiohydrazone have been paid much less attention [6]. As a continuation of our research, the title complex was synthesized and characterized by X-ray diffraction.…”

“…In the past few decades, thiosemicarbazones (TSCs) and their metal complexes have been of interest to chemists and biologists because of their wide range of pharmacological effects [3][4][5][6]. Our previous work shows that copper(II) and nickel(II) complexes of TSCs bearing pyrrole unit have potential antitumor activity [5].…”

Electronic Fine‐Tuning of Oxygen Atom Transfer Reactivity of cis‐Dioxomolybdenum(VI) Complexes with Thiosemicarbazone Ligands

“…The research area has recently been reviewed. [24] In particular, thiosemicarbazones derived from salicylaldehydes allow a systematic investigation of the effect of electron-withdrawing groups (EWGs) or electron-donating groups (EDGs) on the electronic properties of a coordinated molybdenum center. It was found that these electronic trends are reflected in the spectroscopic properties of the molybdenum complexes formed, [18,25] and in their catalytic, [26] biological, [27,28] and pharmacological properties.…”