Body Weight Reduction and Biochemical Parameters of the Patients After RYGB and SG Bariatric Procedures in 12-Month Observation

Abstract

BackgroundThe aim of this study was to evaluate the effect of sleeve gastrectomy (SG) and Roux-en-Y-bypass (RYGB) on anthropometric and biochemical parameters, including changes in glucose levels, lipid profile and liver function. Drastic decrease in all lipid fractions a few weeks or months after the surgery could be regarded as favourable, but low level of HDL is an independent risk factor for heart diseases. Extreme load on the liver without preparation of the patient to the surgery can have negative consequences.MethodsThe test group comprised of 40 female patients at the age of 42.96 with average body weight of 131.56 kg and BMI 46.49. Biochemical analyses were performed using calorimetric method.ResultsNo statistically significant differences were observed in glucose levels between the two types of procedures. The highest differences were noted for triglycerides levels, which decreased, as well as all cholesterol fractions, after RYGB, but were increasing during the first months after SG procedure. Changes in lipid profile, caused by the reduction of all lipid fractions, were more visible after RYGB. The decrease in total cholesterol directly and activity of liver enzymes after the procedure was as higher after RYGB as after SG. Increased activity of transaminases indicates significant liver overload.ConclusionsWith the selection of groups of patients with similar initial parameters, it is not clear whether the differences between the two procedures when assessing the improvement of glycaemia are significant. However, due to invasive character of RYGB, liver overload lasting several months and lifelong limited absorption of nutrients, the possibility of SG procedure should be considered as a first option.

Risk factors for early postoperative complications after bariatric surgery

“…In this institution, there were steadily increasing numbers of patients undergoing SG from 2010 to 2015. Nevertheless, it seems difficult to form solid conclusions about the superiority of SG or RYGB in efficacy and feasibility due to confounding conclusions from previous publications [ 4 5 6 7 8 9 ]. Many studies report better safety profiles in SG than in RYGB [ 4 5 19 20 ].…”

“…Because of a shortened operative time, the lack of anastomoses and the decreased extent of dissection, SG is usually regarded as a simpler and less invasive procedure than RYGB [ 1 2 3 ]. However, there has been ongoing debate concerning procedural superiority in terms of complication rates or mortality, as well as in terms the efficacy in weight loss and resolution of metabolic comorbidities [ 4 5 6 7 8 9 ].…”

Comparıson of Weıght and Body Composıtıon Change in Person Usıng and Non-Usıng Proteın Powder İn the Fırst 6 Months Perıod after Barrıer Surgery

“…Triglyceride values decreased after all the cholesterol fractions after RGB, but showed an increase in the first months after SG treatment. However, because of the invasive character of RYGB, lifetime limited absorption of nutrients; SG procedure should be considered as the first option [27].…”

The Effect of Bariatric Surgery on Weight Loss and Metabolic Changes in Adults with Obesity

“…LRYGB was associated with the greatest reduction in the concentration of total cholesterol and Low-Density Lipoproteins (LDL-cholesterol) in plasma, while SG influenced the concentration of High-Density Lipoproteins (HDL-cholesterol) to the greatest extent. Szczuko et al [19] did not observe statistically significant differences in glucose concentrations after the LRYGB and SG procedures. The highest differences were observed for triglycerides and all cholesterol fractions, which decreased after LRYGB but increased in the first months after SG surgery.…”