Body temperature as a predictor of mortality in COVID-19

Abstract

It remains uncertain if body temperature (BT) is a useful prognostic indicator in coronavirus disease 2019 (COVID-19). We investigated the relationship between BT and mortality in COVID-19 patients. We used a de-identified database that prospectively collected information from patients screened for COVID-19 at the Mount Sinai facilities from February 28, 2020 to July 28, 2021. All patients diagnosed with COVID-19 that had BT data were included. BT at initial presentation, maximum BT during hospitalization, comorbidity, and vaccination status data were extracted. Mortality rate was assessed as a primary outcome. Among 24,293 cases, patients with initial BT below 36 °C had higher mortality than those with BT of 36–37 °C (p < 0.001, odds ratio 2.82). Initial BT > 38 °C was associated with high mortality with an incremental trend at higher BT. In 10,503 in-patient cases, a positive association was observed between mortality and maximum BT except in patients with BT < 36 °C. Multiple logistic regression analyses including the comorbidities revealed that maximum BT was an independent predictor of mortality. While vaccination did not change the distribution of maximum BT, mortality was decreased in vaccinated patients. Our retrospective cohort study suggests that high maximum BT is an independent predictor of higher mortality in COVID-19 patients.

Predicting COVID-19 Hospital Stays with Kolmogorov–Gabor Polynomials: Charting the Future of Care

“…The comorbidities score was significantly higher in patients with longer LOS (p-value < 0.05, Table 1). The cutoffs used for high-risk exposures were provided by the following: age [48], body temperature [49], heart rate [50,51], blood pressure [52], oxygen saturation [53], neutrophils, lymphocytes, hemoglobin, platelets, D-dimer [54], ferritin [55], CRP [56], ESR [57], LDH [58], AST [59], ALT [60], and creatinine [61]. a The Chi-square test was utilized for binary variables to compare proportions between the two independent groups.…”