Body Size Indexes for Optimizing Iodine Dose for Aortic and Hepatic Enhancement at Multidetector CT: Comparison of Total Body Weight, Lean Body Weight, and Blood Volume

Kondo, Hiroshi; Kanematsu, Masayuki; Goshima, Satoshi; Tomita, Yuhei; Kim, Do Young; Moriyama, Noriyuki; Onozuka, Minoru; Shiratori, Yoshimune; Bae, Kyongtae T.

doi:10.1148/radiol.09090369

Cited by 82 publications

(86 citation statements)

References 22 publications

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“…Although patients < age 16 years were excluded from this trial, the patients were not otherwise classifi ed by age. Because this trial was planned only to demonstrate a difference, if any, in contrast enhancement between males and females, the body mass index of the patients was not considered and the validity of using LBW 14,15 was treated only as a reference. Additional studies are needed that include more patients and larger amount of contrast material and that classify patients according to age and body mass index as well as LBW.…”

Section: Discussionmentioning

confidence: 99%

Should the dose of contrast medium be determined solely on the basis of body weight regardless of the patient’s sex?

et al. 2011

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Section: Discussionmentioning

confidence: 99%

Should the dose of contrast medium be determined solely on the basis of body weight regardless of the patient’s sex?

et al. 2011

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“…Thus, it is affected by the total volume of CM. It can be modulated on the basis of iodine concentration: The higher the iodine concentration, the lower the volume of injected CM (1,5,31). For example, to achieve optimal parenchymal enhancement of the liver (around 50-60 HU), it is necessary to deliver around 500-750 mgI per kg of body weight (1).…”

Section: Discussionmentioning

confidence: 99%

“…For example, to achieve optimal parenchymal enhancement of the liver (around 50-60 HU), it is necessary to deliver around 500-750 mgI per kg of body weight (1). Conversely, vascular enhancement is directly dependent on the iodine delivery rate, which is the iodine load given per unit of time (1,5).…”

Section: Discussionmentioning

confidence: 99%

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Analysis of the Effects of Different Iodine Concentrations on the Characterization of Small Renal Lesions Detected by Multidetector Computed Tomography Scan: A Pilot Study

Lee

Kim

Cho

et al. 2017

J Korean Soc Radiol

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Multidetector computed tomography (MDCT) of the abdominal solid organs, including the liver and kidney, is an essential imaging modality of routine clinical practice for the diagnosis, treatment planning, and follow-up of many diseases. The diagnostic accuracy of CT examination is highly dependent on the imaging protocols and, in particular, on contrast media (CM) Purpose: Our objective was to compare the effects of different iodine concentrations on characterizing small renal lesions. Materials and Methods: Thirty-eight patients were enrolled in this study. All patients underwent an initial CT scan using 370 mgI/mL iodinated contrast media. Patients were then randomized into two groups for a follow-up CT. Group A (n = 19) received 250 mgI/mL iodinated contrast media, and group B (n = 19) received 300 mgI/mL contrast media. The mean Hounsfield units (HU values) of small renal lesions with a maximum size of less than 2 cm were calculated. Signal to noise ratios (SNR values) were likewise evaluated. Three uroradiologists assessed the lesion's conspicuity and the diagnostic influence of the artifact's proximity to the adjacent renal parenchyma. Results: In group A, there were significant differences between the HU values of renal lesions and those of the adjacent renal parenchyma between the initial and follow-up CT. Conversely, in group B, there was no significant difference. Moreover, SNR values showed no statistically significant difference between both groups. Regarding lesion conspicuity, only one reader identified a significant difference (p = 0.032) in group A; whereas in group B, there was no statistical difference. The artifact's proximity to the adjacent renal parenchyma did not appear to have any diagnostic influence on differentiating the two (p < 0.05). Conclusion:In evaluating small renal lesions, 300 mgI/mL instead of 370 mgI/mL contrast media can be used; however, it is important to note that the use of 250 mgI/ mL contrast media may reveal different results from that of 370 mgI/mL contrast media. Index terms

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“…Lean body weight can also be more directly measured as a third potential indicator to customize contrast dose via the use of a patient body fat monitor. 25,26 These attempts at extending the characterization of patient size and body composition have been developed because the use of total body weight alone may in obese patients ORIGINAL ARTICLE 874 www.jcat.org …”

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confidence: 99%

An Optimal Contrast Dose Indicator for the Determination of Hepatic Enhancement in Abdominal Multidetector Computed Tomography

Li¹,

Udayasankar²,

Tang³

et al. 2010

Journal of Computer Assisted Tomography

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Body Size Indexes for Optimizing Iodine Dose for Aortic and Hepatic Enhancement at Multidetector CT: Comparison of Total Body Weight, Lean Body Weight, and Blood Volume

Abstract: When LBW, rather than TBW or BV, is used, the iodine dose required to achieve consistent hepatic enhancement may be estimated more precisely and with reduced patient-to-patient variability.

Cited by 82 publications

References 22 publications

Should the dose of contrast medium be determined solely on the basis of body weight regardless of the patient’s sex?

Should the dose of contrast medium be determined solely on the basis of body weight regardless of the patient’s sex?

Analysis of the Effects of Different Iodine Concentrations on the Characterization of Small Renal Lesions Detected by Multidetector Computed Tomography Scan: A Pilot Study

An Optimal Contrast Dose Indicator for the Determination of Hepatic Enhancement in Abdominal Multidetector Computed Tomography

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