Body mass index as an indicator of obstructive sleep apnea in pediatric Down syndrome

Shires, Courtney B.; Anold, Sandra L.; Schoumacher, Robert; Dehoff, George W.; Donepudi, Sreekrishna Kanth; Stocks, Rose Mary S.

doi:10.1016/j.ijporl.2010.03.050

Cited by 55 publications

(68 citation statements)

References 11 publications

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“…Specifically, insomnia was associated with poorer verbal fluency, OSA was associated with poorer verbal fluency and inhibitory control, and daytime sleepiness was associated with poor inhibitory control (Chen, Spanò, & Edgin, 2013). The severity of OSA assessed using PSG was related to younger age and obesity among adults with DS, but findings regarding the relationship to obesity have also been inconsistent (Fitzgerald, Paul, & Richmond, 2007; Shires et al, 2010; Telakivi, Partinen, Salmi, Leinonen, & Härkönen, 1987; Trois et al, 2009). …”

Section: Syndrome/condition Specific Sleep Problemsmentioning

confidence: 99%

Sleep in Neurodevelopmental Disorders

Esbensen

Schwichtenberg

2016

International Review of Research in Developmental Disabilities

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Individuals with intellectual and developmental disabilities (IDD) experience sleep problems at higher rates than the general population. Although individuals with IDD are a heterogeneous group, several sleep problems cluster within genetic syndromes or disorders. This review summarizes the prevalence of sleep problems experienced by individuals with Angelman syndrome, Cornelia de Lange syndrome, Cri du Chat syndrome, Down syndrome, fragile X syndrome, Prader-Willi syndrome, Smith-Magenis syndrome, Williams syndrome, autism spectrum disorder, and idiopathic IDD. Factors associated with sleep problems and the evidence for sleep treatments are reviewed for each neurodevelopmental disorder. Sleep research advancements in neurodevelopmental disorders are reviewed, including the need for consistency in defining and measuring sleep problems, considerations for research design and reporting of results, and considerations when evaluating sleep treatments.

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Section: Syndrome/condition Specific Sleep Problemsmentioning

confidence: 99%

Sleep in Neurodevelopmental Disorders

Esbensen

Schwichtenberg

2016

International Review of Research in Developmental Disabilities

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“…The pathophysiological reasons for this are related to both the cranio-facial features of this syndrome; midface hypoplasia and relative macroglossia, as well as generalized hypotonia, lymphoid hyperplasia and preponderance towards obesity [12,13]. A raised BMI appears to correlate strongly with OSA in both groups of patients [14]. Obstructive sleep apnea Trisomy 21 Down's syndrome Post-operative complications Tonsillectomy Adenotonsillectomy…”

Section: Introductionmentioning

confidence: 99%

Comparative outcomes of severe obstructive sleep apnea in pediatric patients with Trisomy 21

Thottam

Trivedi

Siegel

et al. 2015

International Journal of Pediatric Otorhinolaryngology

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“…For patients with a McGill score of 2, with elevated BMI and adenotonsillar hypertrophy, referral to ENT is also likely warranted, as prior studies suggest that BMI may be an indicator of OSDB in children with trisomy 21. 23 Patients with McGill Scores of 1 or 2, without associated obesity or adenotonsillar hypertrophy, will likely require a full overnight polysomnogram in accordance with the general AAP guidelines to establish the level of disease and distinguish obstructive and central events.…”

mentioning

confidence: 99%