Body mass index and outcome of out-of-hospital cardiac arrest patients not treated by targeted temperature management

Galatianou, Ioanna; Karlis, George; Apostolopoulos, A; Intas, Georgios; Chalari, Eleftheria; Gulati, Anil; Iacovidou, Nicoletta; Chalkias, Athanasios; Xanthos, Theodoros

doi:10.1016/j.ajem.2017.03.050

Cited by 14 publications

(10 citation statements)

References 40 publications

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“…The analyzed studies in this meta-analysis have heterogeneous baseline characteristics in terms of race, sample size, and proportion of patients treated with TTM. Galatianou et al included a relatively small number of survivors after cardiac arrest, and the study was conducted at a single center [26]. In one of the included studies, all patients were managed with TTM, and none to one-third of patients underwent TTM in other studies [13].…”

Section: Discussionmentioning

confidence: 99%

“…After reviewing the full-text articles more thoroughly, we excluded 43 studies for irrelevant population (n = 25), irrelevant outcome measure (n = 12), irrelevant control group (n = 4), and meta-analyses (n = 2). The six remaining studies with 2427 patients were included in the meta-analysis [13,17,18,[25][26][27]. The reference management software, Endnote X9 (Clarivate Analytics, Philadelphia, United States), was used for all identified studies in the literature search.…”

Section: Study Selectionmentioning

confidence: 99%

Section: Study Selectionmentioning

confidence: 99%

“…Of the six studies included in this study, three studies were rated as low-quality studies using the quality scoring system defined in the Methods section [25][26][27]. The major factors that affected study quality were attrition bias by incomplete outcome data and reporting bias.…”

Section: Risk Of Bias In Individual Studiesmentioning

confidence: 99%

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Association between Body Mass Index and Outcomes in Patients with Return of Spontaneous Circulation after Out-of-Hospital Cardiac Arrest: A Systematic Review and Meta-Analysis

Lee

Shin

et al. 2021

IJERPH

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Increased body mass index (BMI) is a risk factor for cardiovascular disease, stroke, and metabolic diseases. A high BMI may affect outcomes of post-cardiac arrest patients, but the association remains debatable. We aimed to determine the association between BMI and outcomes in patients with return of spontaneous circulation (ROSC) after out-of-hospital cardiac arrest (OHCA). A systematic literature search was conducted using MEDLINE, EMBASE, and the Cochrane Library. Studies that included patients who presented ROSC after OHCA, had a recorded BMI, and were assessed for neurological outcomes and in-hospital mortality were included. To assess the risk of bias of each included study, we employed the Risk of Bias Assessment Tool for Non-randomized Studies. We assessed 2427 patients from six studies. Neurological outcomes were significantly poorer in underweight patients (risk ratio (RR) = 1.21; 95% confidence interval (CI) = 1.07–1.37; p = 0.002; I2 = 51%) than in normal-weight patients. Additionally, in-hospital mortality rate was significantly higher in underweight patients (RR = 1.35; 95% CI = 1.14–1.60; p<0.001; I2 = 21%) and in obese patients (RR = 1.25; 95% CI = 1.12–1.39; p<0.001; I2 = 0%) than in normal-weight patients. Poor neurological outcome is associated with underweight, and low survival rate is associated with underweight and obesity in patients with ROSC after OHCA.

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Section: Discussionmentioning

confidence: 99%

Section: Study Selectionmentioning

confidence: 99%

Section: Study Selectionmentioning

confidence: 99%

Section: Risk Of Bias In Individual Studiesmentioning

confidence: 99%

See 2 more Smart Citations

Association between Body Mass Index and Outcomes in Patients with Return of Spontaneous Circulation after Out-of-Hospital Cardiac Arrest: A Systematic Review and Meta-Analysis

Lee

Shin

et al. 2021

IJERPH

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“…In particular, Galatianou et al reported a 15.5% of patients who came at the Emergency Department and returned to systemic circulation, entered the intensive care unit and remained on average 6.7 ± 4.9 days. 21 Subsequently, Karagiannis et al, in a research study they carried out at the Nicosia General Hospital of Cyprus, reported a 44% return of victims to automatic circulation in the Emergency Department, after cardiac arrest. 22 The survival rates of the two surveys differ, although both are low, as well as at a global level.…”

Section: Introductionmentioning

confidence: 99%

Survival rate of incoming patients with cardiac arrest at the cardiology infirmary of the emergency department of a public hospital in Greece

et al. 2019

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Introduction: Cardiac arrest is an urgent situation that, despite the improved resuscitation capabilities, the survival rate of out-of-hospital cardiac arrest victims remains low.Aim: Τo investigate the survival rate of the incoming patients with cardiac arrest in the cardiology infirmary of the emergency department of a public hospital.Material-Method: The study included 210 patients who were transferred pulseless and breathless at the cardiology infirmary of the emergency department of “Tzaneio” Hospital, Piraeus, during the period April 2017 - November 2018. Data was collected from the National Center of Emergency Dispatch's printed forms, as well as from the patients’ admission book of the emergency department.Results: More than 10% (11.9%) of patients with cardiac arrest returned to spontaneous circulation in the emergency department, of which 16% was discharged. Patients with known cardiac history, (p=0.002), with a shockable rhythm (p<0.001), and especially ventricular fibrillation (p<0.001) upon arrival at the emergency room, and patients who were defibrillated at the ambulance during admission and at the emergency room, were more likely to survive (p<0.001). No statistically significant correlation was found between the factors studied and survival after cardiac arrest, in the group of patients that were discharged.Conclusions: The survival rate of the incoming patients with cardiac arrest at the emergency department of “Tzaneio” Hospital, Piraeus, was low. As for most health systems, this issue constitutes a fairly complex public health problem. Cardiopulmonary resuscitation and corresponding guidelines require further improvement in order for the survival rates of out-of-hospital cardiac arrest patients to increase.

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The effect of thoracic dimensions on compression depth during cardiopulmonary resuscitation

Moradicheghamahi

Fortuny

López

et al. 2023

Numer Methods Biomed Eng

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The effect of the dimensions of the thoracic cage on the resuscitation outcome of cardiopulmonary resuscitation (CPR) maneuvers has long been debated. In this study, the effect of changes in the rib cage dimensions on the achieved compression depth was investigated using finite element simulations. A total of 216 different rib cage geometry models were considered and, in each case, the result of applying different levels of compression force up to 600 N were simulated. The Haller Index of the rib cage is defined as the ratio of the transverse diameter and the antero-posterior diameter. Our results suggest that, with a fixed level of compression force, performing CPR on rib cages having a low Haller Index and/or a larger height leads to compression depths below the average. Alternatively, if a target compression depth is set for CPR, in general a lower compression force would be required for individuals with higher Haller Index and/or lower chest height. In addition, present results indicate that wider chested individuals will experience lower stress levels on their ribs to achieve the required CPR target depth. Moreover, in the present study we propose predictive models, based on anthropometric parameters, for compression depth and rib stress during chest compressions. In particular, the model suggests that in future correlations of empirical CPR data the patients' Haller index and vertical (sagittal) cross-area are the best parameters to be used as independent variables in a fit.

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Body mass index and outcome of out-of-hospital cardiac arrest patients not treated by targeted temperature management

Cited by 14 publications

References 40 publications

Association between Body Mass Index and Outcomes in Patients with Return of Spontaneous Circulation after Out-of-Hospital Cardiac Arrest: A Systematic Review and Meta-Analysis

Association between Body Mass Index and Outcomes in Patients with Return of Spontaneous Circulation after Out-of-Hospital Cardiac Arrest: A Systematic Review and Meta-Analysis

Survival rate of incoming patients with cardiac arrest at the cardiology infirmary of the emergency department of a public hospital in Greece

The effect of thoracic dimensions on compression depth during cardiopulmonary resuscitation

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