Body mass index and mortality in China: a 15-year prospective study of 220 000 men

Abstract

For China, previous evidence may have overestimated the excess mortality at low BMI but underestimated that at high BMI. The main way obesity kills in China appears to be stroke.

Changes in BMI Before and During Economic Development and Subsequent Risk of Cardiovascular Disease and Total Mortality: A 35-Year Follow-up Study in China

“…Five prospective studies conducted in mainland China, three based on BMI measured in the 1980s (12)(13)(14) and two in 1991 (15,16), showed that both underweight and obesity were associated with increased mortality in the Chinese adult population. These results were similar to our findings based on BMI measured in 1994.…”

“…The association between BMI and all-cause mortality showed J-shaped (8,9) or U-shaped (10-16) relationships in recent studies, including a recently pooled analysis of prospective data from the Asia Cohort Consortium (7) and five cohort studies from mainland China (12)(13)(14)(15)(16). However, nearly all previous reports used a single measurement (i.e., baseline), ignoring the changes during rapid economic development of these countries (5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16).…”

“…The association between BMI and all-cause mortality showed J-shaped (8,9) or U-shaped (10-16) relationships in recent studies, including a recently pooled analysis of prospective data from the Asia Cohort Consortium (7) and five cohort studies from mainland China (12)(13)(14)(15)(16). However, nearly all previous reports used a single measurement (i.e., baseline), ignoring the changes during rapid economic development of these countries (5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16). Some cohort studies have examined the association between weight or BMI change and subsequent mortality (17)(18)(19)(20)(21)(22)(23), but the duration of follow-up was typically short (,10 years) and methodological biases are common, such as confounding by smoking and pre-existing diseases (16,20,24).…”

The influence of rs2273773 and rs7895833 SIRT1 gene polymorphisms on life expectancy in context of metabolic factors in Silesian population

“…Another large 15-year prospective study of 220.000 Chinese people also demonstrated the impact of an increased BMI on life expectancy. It was estimated that any increase in BMI by 5 kg/m 2 gives a mortality risk of 14-27% [26]. It is difficult to choose a control group based on such a parameter which will inevitably indicate that the group will not live to a specific age.…”

“…W innym dużym, 15-letnim badaniu prospektywnym na populacji 220 000 chińczyków rów-nież wykazano wpływ zwiększonego BMI na długość życia. Oszacowano, że każdy wzrost BMI o 5 kg/m 2 daje ryzyko śmiertelności w granicach 14-27% [26]. Trudno dobrać grupę kontrolną opartą na takim parametrze, który w sposób pewny wskaże, że grupa ta nie dożyje konkretnego wieku.…”