Body Height, Cardiovascular Risk Factors, and Risk of Stroke in Middle-aged Men and Women

Njølstad, Inger; Arnesen, Egil; Lund‐Larsen, Per G.

doi:10.1161/01.cir.94.11.2877

Cited by 115 publications

(94 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…[7][8][9]11,29 One study even showed higher SBP in taller subjects. 30 Something similar occurs in the case of DBP.…”

Section: Pulse Systolic and Diastolic Blood Pressure In Older Peoplementioning

confidence: 99%

“…1 In contrast, the evidence as to whether childhood socioeconomic circumstances and height are related to blood pressure -one of the main coronary risk factors -in adulthood has been inconsistent: some studies find a relation, 2-6 while others do not. [7][8][9][10][11][12] Some studies that have found an association between childhood social class and adult blood pressure have shown that the association decreases or disappears after adjusting for body mass index in adulthood. 3,6 Given the strong association between obesity and blood pressure, these findings suggest that obesity is the factor that mediates the relation between childhood social class and adult blood pressure.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Influence of childhood socioeconomic circumstances, height, and obesity on pulse pressure and systolic and diastolic blood pressure in older people

et al. 2005

View full text Add to dashboard Cite

This study assesses the association of childhood socioeconomic circumstances, height, and obesity with components of blood pressure. We selected 4009 people representative of the Spanish population aged 60 years and older, and estimated systolic blood pressure (SBP), diastolic blood pressure (DBP), and pulse pressure (PP) according to childhood social class, height, and obesity. No association was found between childhood social class and blood pressure. SBP showed an inverse gradient and DBP a direct gradient with height, although an independent association between height and DBP was found only in women. Stature was independently associated with increased DBP in women with central obesity, but there was no association between height and DBP in women without central obesity. Short stature was independently associated with increased PP. Body mass index and waist-to-hip ratio were independently associated with increased DBP in women, and waist-to-hip ratio was independently associated with increased PP in men, while waist circumference was independently associated with increased DBP and increased PP in women. These results do not support the assumed effect of socioeconomic circumstances in early life on blood pressure, which may depend on the context and/or study population. The relations observed between height and blood pressure support the hypothesis that PP could be a mediator of the association between short stature and increased cardiovascular risk. The relationship between obesity measures and components of blood pressure reinforces the recommendation to reduce body weight in order to reduce blood pressure.

show abstract

“…[7][8][9]11,29 One study even showed higher SBP in taller subjects. 30 Something similar occurs in the case of DBP.…”

Section: Pulse Systolic and Diastolic Blood Pressure In Older Peoplementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Influence of childhood socioeconomic circumstances, height, and obesity on pulse pressure and systolic and diastolic blood pressure in older people

et al. 2005

View full text Add to dashboard Cite

show abstract

“…46 The association between high NEFA concentration and stroke may be easier to explain. Hypertension is a strong predictor of stroke 47 and has been associated with high NEFA concentrations and impaired action of insulin on NEFA metabolism. 16,48 In support of this, in the multiple regression analysis SBP was independently associated with NEFA concentration in nondiabetic women.…”

Section: Carlsson Et Al Nonesterified Fatty Acids and Familial Cvdmentioning

confidence: 99%

High Levels of Nonesterified Fatty Acids Are Associated With Increased Familial Risk of Cardiovascular Disease

Carlsson

Wessman

Almgren

et al. 2000

ATVB

102

View full text Add to dashboard Cite

show abstract

“…Hence, stroke represents a major public health problem as well as a heavy socioeconomic burden for society [1]. Although stroke is in part preventable through intervention against several established risk factors, the association between a high body mass index (BMI) and stroke remains controversial, with either positive [2] or null [3] associations reported. Some authors suggested, however, that high BMI may not be the most informative measure of obesity with respect to risk of stroke [4] and myocardial infarction [5].…”

Section: Introductionmentioning

confidence: 99%

Prospective study of body size and risk for stroke amongst women below age 60

Lü

Adami

et al. 2006

Journal of Internal Medicine

View full text Add to dashboard Cite

The relation between obesity, particularly abdominal obesity, and risk of stroke amongst women remains unclear. In 1991-1992, a prospective study was initiated in Sweden amongst women who returned a self-administered questionnaire. Through linkage with nation-wide registries, 45 449 women, free of stroke at entry, were followed up until diagnosis of first incident stroke, death, or the end of follow-up in 2002. We estimated multivariate relative risks (RRs) with 95% confidence intervals (CIs) from Cox proportional hazards regression models. A total of 170 incident stroke cases occurred during an average of 11 years of follow-up. The RR of stroke amongst women in the highest compared with the lowest quintile was 2.4 (95% CI 1.3-4.2; P for trend 0.04) for waist-to-hip ratio, 2.5 (95% CI 1.5-4.3; P for trend 0.01) for waist-to-height ratio and 2.3 (95% CI 1.2-4.3; P for trend 0.02) for waist circumference. Adjustment for hypertension and diabetes attenuated these risk estimates. In contrast, birth weight, body mass index (BMI) at age 18, BMI at entry, weight change in adulthood and adult height were not significantly associated with risk of stroke. This study provides evidence that, in contrast to BMI, several different measures of abdominal obesity are strong predictors of stroke in women.

show abstract

Body Height, Cardiovascular Risk Factors, and Risk of Stroke in Middle-aged Men and Women

Abstract: The results are consistent with the theory that factors influencing early growth as well as adult lifestyle factors contribute to cerebrovascular disease in adult age.

Cited by 115 publications

References 37 publications

Influence of childhood socioeconomic circumstances, height, and obesity on pulse pressure and systolic and diastolic blood pressure in older people

Influence of childhood socioeconomic circumstances, height, and obesity on pulse pressure and systolic and diastolic blood pressure in older people

High Levels of Nonesterified Fatty Acids Are Associated With Increased Familial Risk of Cardiovascular Disease

Prospective study of body size and risk for stroke amongst women below age 60

Contact Info

Product

Resources

About