Body fat accumulation and postoperative morbidity in colorectal-cancer surgery

Tsukada, Katsuhiko; Miyazaki, Tatsuya; Katoh, Hiroyuki; Masuda, Norihiro; Ojima, Hitoshi; Fukuchi, Minoru; Manda, Ryokuhei; Fukai, Yasuyuki; Nakajima, Masahiro; Ishizaki, Masatoshi; Motegi, Masahiko; Ohsawa, Hajime; Mogi, Akira; Okamura, Akihiko; Tsunoda, Yuko; Sohda, Makoto; Ohno, Tetsuro; Moteki, Takao; Sekine, Yuji; Kuwano, Hiroyuki

doi:10.1007/s10353-005-0141-8

Cited by 29 publications

(42 citation statements)

References 22 publications

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“…The main reasons for this might be differences in anatomy between the cervical and thoracic spine with a different curvature and different muscle-fat ratios. It is possible that SFT is of importance in areas where there is more soft tissue than rostral to the thoracic spine [10,19,20].…”

Section: Discussionmentioning

confidence: 99%

Role of Pre-Operative Blood Transfusion and Subcutaneous Fat Thickness as Risk Factors for Surgical Site Infection after Posterior Thoracic Spine Stabilization

Osterhoff

Burla

Werner

et al. 2015

Surgical Infections

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BACKGROUND Surgical site infections (SSIs) increase morbidity and mortality rates and generate additional cost for the healthcare system. Pre-operative blood transfusion and the subcutaneous fat thickness (SFT) have been described as risk factors for SSI in other surgical areas. The purpose of this study was to assess the impact of pre-operative blood transfusion and the SFT on the occurrence of SSI in posterior thoracic spine surgery. METHODS In total, 244 patients (median age 55 y; 97 female) who underwent posterior thoracic spine fusions from 2008 to 2012 were reviewed retrospectively. Patientspecific characteristics, pre-operative hemoglobin concentration/hematocrit values, the amount of blood transfused, and the occurrence of a post-operative SSI were documented. The SFT was measured on pre-operative computed tomography scans. RESULTS Surgical site infection was observed in 26 patients (11%). The SFT was 13 mm in patients without SSI and 14 mm in those with infection (p=0.195). The odds ratio for patients with pre-operative blood transfusion to present with SSI was 3.1 (confidence interval [CI] 1.4-7.2) and 2.7 (CI 1.1-6.4) when adjusted for age. There was no difference between the groups with regard to pre-operative hemoglobin concentration (p=0.519) or hematocrit (p=0.908). The SFT did not differ in the two groups. CONCLUSIONS Allogeneic red blood cell transfusion within 48 h prior to surgery was an independent risk factor for SSI after posterior fusion for the fixation of thoracic spine instabilities. Pre-operative blood transfusion tripled the risk, whereas SFT had no influence on the occurrence of SSI. Background: Surgical site infections (SSIs) increase morbidity and mortality rates and generate additional cost for the healthcare system. Pre-operative blood transfusion and the subcutaneous fat thickness (SFT) have been described as risk factors for SSI in other surgical areas. The purpose of this study was to assess the impact of pre-operative blood transfusion and the SFT on the occurrence of SSI in posterior thoracic spine surgery. Methods: In total, 244 patients (median age 55 y; 97 female) who underwent posterior thoracic spine fusions from 2008 to 2012 were reviewed retrospectively. Patient-specific characteristics, pre-operative hemoglobin concentration/hematocrit values, the amount of blood transfused, and the occurrence of a post-operative SSI were documented. The SFT was measured on pre-operative computed tomography scans.Results: Surgical site infection was observed in 26 patients (11%). The SFT was 13 mm in patients without SSI and 14 mm in those with infection (p = 0.195). The odds ratio for patients with pre-operative blood transfusion to present with SSI was 3.1 (confidence interval [CI] 1.4-7.2) and 2.7 (CI 1.1-6.4) when adjusted for age. There was no difference between the groups with regard to pre-operative hemoglobin concentration (p = 0.519) or hematocrit (p = 0.908). The SFT did not differ in the two groups. Conclusions: Allogeneic red blood cell transfusion within 48 h p...

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Section: Discussionmentioning

confidence: 99%

Role of Pre-Operative Blood Transfusion and Subcutaneous Fat Thickness as Risk Factors for Surgical Site Infection after Posterior Thoracic Spine Stabilization

Osterhoff

Burla

Werner

et al. 2015

Surgical Infections

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“…However, there is a little data on the value of these indices in surgery of any type. As demonstrated by the results in the previously described Japanese study, 115 the assessment of abdominal obesity, even using simple measures, such as waist:hip ratio, is warranted in future studies.…”

Section: Problems With Previous Researchmentioning

confidence: 93%

“…In multilogistic regression analysis, high SCF emerged as a highly significant risk factor with an OR of 10 (P=0.003). It should be emphasized that gastric and colorectal procedures were combined in this study 115 and obesity is less common among the Japanese. Nevertheless, the use of direct measures of abdominal adiposity and the strength of association strengthens the argument that it is central obesity, rather than absolute body weight or BMI, that is hazardous to health.…”

Section: Overall Morbidity and Mortalitymentioning

confidence: 96%

The Impact of Obesity on Outcome after Major Colorectal Surgery

Gendall¹,

Raniga²,

Kennedy³

et al. 2007

Diseases of the Colon &Amp; Rectum

195

147

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“…Obesity is an independent risk factor for anastomotic leak (AL) and increase the risk of leakage up to 2.7 times when compared with non-obese patients 6,15 ; this association has many hypotheses like tissue stricture and healing defect, increase of intraabdominal pressure and microcirculation damage. Nutritional status is another important factor.…”

Section: Major Factors Affecting Healing Process In Colorectal Anastomentioning

confidence: 99%

Ghrelin and gastrointestinal wound healing. A new perspective for colorectal surgery

et al. 2018

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Body fat accumulation and postoperative morbidity in colorectal-cancer surgery

Cited by 29 publications

References 22 publications

Role of Pre-Operative Blood Transfusion and Subcutaneous Fat Thickness as Risk Factors for Surgical Site Infection after Posterior Thoracic Spine Stabilization

Role of Pre-Operative Blood Transfusion and Subcutaneous Fat Thickness as Risk Factors for Surgical Site Infection after Posterior Thoracic Spine Stabilization

The Impact of Obesity on Outcome after Major Colorectal Surgery

Ghrelin and gastrointestinal wound healing. A new perspective for colorectal surgery

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