Body Distribution, Turnover Rate, and Radiation Dose after the Parenteral Administration of Radiovitamin B<sub>12</sub><sup>1</sup>

Reizenstein, Peter

doi:10.1111/j.0954-6820.1959.tb14522.x

Cited by 19 publications

(4 citation statements)

References 36 publications

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“…The biological half-life of B12 is approximately 1 y (17)(18)(19), and this is the reason why raising animals in B12-deficiency is difficult, especially in a short period. We have learned that it takes more than 90 d to induce B12-deficiency in mature rats by feeding the soy proteinbased B12-deficient diet after weaning (5,10).…”

Section: Discussionmentioning

confidence: 99%

Influences of Maternal B12 and Methionine Intake during Gestation and Lactation on Testicular Development of Offspring in Rats

Yamada

Maeda

Noguchi

et al. 2013

J Nutr Sci Vitaminol

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The influence of maternal vitamin B₁₂ malnutrition on testicular development of offspring was examined using soy protein-based B₁₂-deficient diets with or without 0.5% DL-methionine supplementation. Dams were fed the B₁₂-deficient diet throughout gestation and lactation, whereas dams in a control group were fed a control diet which contained cyanocobalamin in the B₁₂-deficient diet without methionine. Offspring born to dams fed the B₁₂-deficient diet without methionine showed poor testicular development, e.g. decreased numbers of seminiferous tubules containing healthy spermatocytes and a high ratio of apoptotic cells per all germ cells. The abnormality was rarely observed in the group fed the B₁₂-deficient diet with methionine. It was likely that the testicular abnormality of offspring was caused by B₁₂-deficiency post partum and was prevented by the methionine supplementation. These observations suggested that maternal B₁₂ nutritional status during the pre-weaning period is quite important for spermatogenesis of male offspring and that the requirement of B₁₂ for testicular development is to produce active B₁₂-dependent methionine synthase.

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Section: Discussionmentioning

confidence: 99%

Influences of Maternal B12 and Methionine Intake during Gestation and Lactation on Testicular Development of Offspring in Rats

Yamada

Maeda

Noguchi

et al. 2013

J Nutr Sci Vitaminol

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“…We have assumed that a dynamic equilibrium exists between the plasma and tissue pools and that the serum vitamin B,, concentration measures all vitamin B,, pools. O n the other hand, it has been suggested that the turnover of vitamin B,, is best described as an open system, which includes one or more compartments with slow turnover rates, and that in such a system equilibrium will not be attained in a finite time (10,11). In seruni, which is considered to be the transport pool, the turnover rate is rapid.…”

Section: Discussionmentioning

confidence: 99%

Calculations on the Dynamics of Vitamin B₁₂in Fish Tapeworm Carriers Spontaneously Recovering from Vitamin B₁₂Deficiency

Nyberg

Saarni

1964

Journal of Internal Medicine

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“…and here the slope of this function is given. Jn othcr cases, thcse cunes dcscribed multiple expo nential functions, and here the slope is ghcn for the first of the expone111ial func1ions, which was obtained by the graphic subtraction method previously described (7).…”

Section: In Thc Retrospectit)e Part Information Was Taken From the Casementioning

confidence: 99%

Hematological changes in psoriasis. Secondary anemia, XVIII

Molin¹,

Reizenstein²

1974

Acta Derm Venereol

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Body Distribution, Turnover Rate, and Radiation Dose after the Parenteral Administration of Radiovitamin B₁₂¹

Cited by 19 publications

References 36 publications

Influences of Maternal B12 and Methionine Intake during Gestation and Lactation on Testicular Development of Offspring in Rats

Influences of Maternal B12 and Methionine Intake during Gestation and Lactation on Testicular Development of Offspring in Rats

Calculations on the Dynamics of Vitamin B₁₂in Fish Tapeworm Carriers Spontaneously Recovering from Vitamin B₁₂Deficiency

Hematological changes in psoriasis. Secondary anemia, XVIII

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Body Distribution, Turnover Rate, and Radiation Dose after the Parenteral Administration of Radiovitamin B121

Cited by 19 publications

References 36 publications

Influences of Maternal B12 and Methionine Intake during Gestation and Lactation on Testicular Development of Offspring in Rats

Influences of Maternal B12 and Methionine Intake during Gestation and Lactation on Testicular Development of Offspring in Rats

Calculations on the Dynamics of Vitamin B12in Fish Tapeworm Carriers Spontaneously Recovering from Vitamin B12Deficiency

Hematological changes in psoriasis. Secondary anemia, XVIII

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Body Distribution, Turnover Rate, and Radiation Dose after the Parenteral Administration of Radiovitamin B₁₂¹

Calculations on the Dynamics of Vitamin B₁₂in Fish Tapeworm Carriers Spontaneously Recovering from Vitamin B₁₂Deficiency