Body composition of rats in B-vitamin deficiencies

Guggenheim, K.; Diamant, E. J.

doi:10.1079/bjn19590009

Cited by 22 publications

(11 citation statements)

References 17 publications

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“…Analysis of paired data gave a mean difference of 12.38 mg of proltein/g wet weight with a t value greater than 15.8. Since the overall liver protein concentration remains unchanged in riboflavin deficiency (20,21), this implies that the nonmitochondrial liver protein must decrease. It is possible that some of the increased mitochondrial protein might be due to de novo synthesis of enzyme proteins, either pyruvate carboxylase or other mitochondrial Table 11.…”

Section: Materials Animals and Diet Malementioning

confidence: 98%

“…Rats were fasted overnight, killed by decapitation, and profuse bleeding was encouraged. The abdominal cavity was opened, the liver was removed, weighed and plaiced in ice-cold homogenization medium containing 0.25 M sucrose, 1 mil4 EDTA, 1 mM reduced glutathione (GSH), 20 growth. The riboflavin-deficient group was allowed continuous access t o a commercial riboflavin-deficient diet.…”

Section: Materials Animals and Diet Malementioning

confidence: 99%

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The Effect of Riboflavin Deficiency on Key Gluconeogenic Enzyme Activities in Rat Liver

Garthoff¹,

Garthoff²,

Tobin³

et al. 1973

Experimental Biology and Medicine

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Section: Materials Animals and Diet Malementioning

confidence: 98%

Section: Materials Animals and Diet Malementioning

confidence: 99%

The Effect of Riboflavin Deficiency on Key Gluconeogenic Enzyme Activities in Rat Liver

Garthoff¹,

Garthoff²,

Tobin³

et al. 1973

Experimental Biology and Medicine

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“…Induction of riboflavin deficiency has been found to cause enlargement of liver (1)(2)(3)(4)(5), but the concentration of nitrogen or protein in liver remained unaffected in riboflavin deficiency (1,5). There was, however, a decrease in the nitrogen content of the carcass, principally that of muscle (1).…”

mentioning

confidence: 93%

“…There was, however, a decrease in the nitrogen content of the carcass, principally that of muscle (1). Further, Chatterjee and Ghosh (6,7) reported increased free amino acid nitro gen concentrations in muscle and also in plasma and liver in riboflavin deficiency.…”

mentioning

confidence: 99%

Effect of Protein Depletion and Subsequent Repletion on Protein Metabolism in Muscle of Riboflavin-deficient Rats

Chatterjee¹,

Ghosh²

1971

J. Vitaminol

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The effects of riboflavin deficiency on muscle protein, RNA and DNA, and on the incorporation of 14C-amino acid into muscle proteins have been studied on rats receiving 16% protein diet, or 16% protein diet followed by protein-free diet or 16% protein diet followed by protein-free diet and 40% protein diet. In each of the dietary conditions, protein content, RNA/DNA and protein/DNA ratios in muscle were found to be decreased in riboflavin deficiency. The incorporation of 14C-amino acid into muscle proteins decreased in riboflavin-deficient rats receiving either 16% protein or 16% protein diet followed by protein-free diet and 40% protein diet. But in riboflavin-deficient rats receiving protein-free diet following 16% protein diet, the incorporation of 14C-amino acid into muscle proteins was found to be enhanced. It has been suggested from these studies that decreased protein content in muscle of riboflavin-deficient rats in each of the dietary conditions is due to both reduced synthesis and increased catabolism of proteins, and the catabolism of muscle proteins in riboflavin-deficient rats is intensive when they receive protein free diet.

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“…It was further noted that induction of ribo flavin deficiency caused liver enlargement but the concentration of nitrogen in liver remained unaltered, and that of the carcass, principally muscle decreased (14).…”

mentioning

confidence: 99%

Effect of Protein Depletion and Subsequent Repletion on In Vivo Incorporation of [14C] Amino Acid into Rat Liver Proteins in Riboflavin Deficiency

Chatterjee¹

1972

J. Vitaminol

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Body composition of rats in B-vitamin deficiencies

Cited by 22 publications

References 17 publications

The Effect of Riboflavin Deficiency on Key Gluconeogenic Enzyme Activities in Rat Liver

The Effect of Riboflavin Deficiency on Key Gluconeogenic Enzyme Activities in Rat Liver

Effect of Protein Depletion and Subsequent Repletion on Protein Metabolism in Muscle of Riboflavin-deficient Rats

Effect of Protein Depletion and Subsequent Repletion on In Vivo Incorporation of [14C] Amino Acid into Rat Liver Proteins in Riboflavin Deficiency

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