Body composition indices and tissue loss in patients with resectable gastric adenocarcinoma

Abstract

Background Body composition analyses from computed tomography (CT) scans have been used to assess cachexia in cancer patients. We investigated body composition indices, tissue change and treatment outcome in patients with resectable gastric adenocarcinoma.

Prognostic value of muscle depletion assessed by computed tomography for surgical outcomes of cancer patients undergoing total esophagectomy and gastrectomy

“…In this study, no significant difference was found between the low MMI in relation to postoperative complications in gastrectomized patients, as well as Aahlin et al that evaluated patients undergoing total and subtotal gastrectomy and its relationship with sarcopenia, assessed by CT images, found no association with surgical outcomes. Tegels et al assessed sarcopenia, also through MMI and found no statistically significant difference for serious complications, length of hospital stay and mortality.…”

“…Several studies in the literature have documented the association between sarcopenia and increased postoperative morbidity and length of stay as well as decreased overall survival in patients with colorectal cancer, but for gastric and esophageal tumors these findings are still controversial. 20 In this study, no significant difference was found between the low MMI in relation to postoperative complications in gastrectomized patients, as well as Aahlin et al 21 It is noteworthy that in the study mentioned above, 21 patients had low muscle index and were not defined as sarcopenics, because they did not meet the other criteria for strength and functionality.…”

Silver linings on the horizon: highlights from the 10th Cachexia Conference

“…Moreover they showed that phase angle was independently associated with skeletal muscle mass, muscle function, and muscle quality in colorectal patients. This buttress the view that the measurement of body mass index is not enough . Most studies used CT scan as valid method to detect muscle wasting .…”

“…This buttress the view that the measurement of body mass index is not enough. 23,24 Most studies used CT scan as valid method to detect muscle wasting. 25 Also Szulc et al 26 (University of Lyon, France) presented data of high resolution pQCT (xtreme CT Scanco) measured in the STRAMBO study.…”

More variety with the Journal of Cachexia, Sarcopenia and Muscle: JCSM Clinical Reports and JCSM Rapid Communications have both gone live

“…For JCSM Clinical Reports, this was about 50% in 2017. Papers that we accepted there included interesting reports on the importance of body mass index in chronic kidney disease 20 and cancer, 21 diagnostic 22 and imaging studies 23 , and a report on exercise training in cancer patients 24 or the social burden of weight loss in lung cancer. 25 The first papers of JCSM Rapid Communications are now also online.…”