Body composition in male rats subjected to early weaning and treated with diet containing flour or flaxseed oil after 21 days until 60 days

Boueri, Bianca Ferolla da Camara; Pessanha, Carolina Ribeiro; Costa, Luanna Rodrigues da; Ferreira, M. R.; Melo, Henrique Saldanha; Abreu, Maíra Duque Coutinho de; Pessoa, Letícia Rozeno; Silva, P. C. Alves da; Pereira, Aline D'Avila; Ribeiro, Danielle Cavalcante; Meneses, J. Azevedo de; Costa, Carlos Alberto Soares da; Boaventura, Gilson Teles

doi:10.1017/s2040174415007163

Cited by 10 publications

(2 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Boueri et al. (2015) also observed lower body weight in early‐weaned male rat pups without a care on PND60. On PND60 pharmacological early weaning did not alter body weight and weight gain of pups; however, we observed a tendency of gradual increase in the body weight and weight gain.…”

Section: Discussionmentioning

confidence: 89%

Early weaning alters redox status in the hippocampus and hypothalamus of rat pups

Klein

August

Santos

et al. 2020

Intl J of Devlp Neuroscience

View full text Add to dashboard Cite

Exposure to environmental factors can program the metabolism, conferring resistance or increasing the risk to chronic disease development in childhood and adulthood. In this sense, lactation is an important period in this window of development. Herein, we investigated the effect of early weaning on neurochemical and behavioral changes in offspring at weaning and adulthood. Female and male pups were divided into four groups: (1) Control weaning (weaning on the PND21, pups were kept with the biological mother); (2) Early Weaning Bromocriptine group (EWB) (pharmacological weaning on PND16); (3) Early Weaning Cross-Fostering group (EWCF) (pups housed with a foster mother on PND16 up to PND21); (4) Early Weaning Without Care group (EWWC) (weaning on PND16, maternal separation). Weight control of pups was recorded from postnatal Day 16 to 59. On the 21st day, part of the pups was euthanized and the hippocampus and hypothalamus were removed for biochemical evaluation. The remaining pups were submitted to behavioral tests on the 60th postnatal day. Early weaning reduced the pups' body weight, in a sexdependent way. At 60 days of age, male pups of EWCF and EWWC groups have lower body weight compared to control male, and female body weight was lower than male pups. In relation to biochemical changes in the brain, weaning altered the levels of oxidants, increased the enzymatic activity of superoxide dismutase (SOD), and glutathione peroxidase (GPx), as well as induced lipid peroxidation. Weaning was also able to alter long-term memory and induce anxious behavior in pups. Our results demonstrate that the different types of early weaning changed the parameters of redox status in the hippocampus and hypothalamus of pups (21 days old), suggesting a prooxidative profile, in addition, to alter learning/memory and inducing an anxious behavior in male offspring (60 days old).

show abstract

Section: Discussionmentioning

confidence: 89%

Early weaning alters redox status in the hippocampus and hypothalamus of rat pups

Klein

August

Santos

et al. 2020

Intl J of Devlp Neuroscience

View full text Add to dashboard Cite

show abstract

“…Composição das dietas experimentais. Niterói-RJ, 2020 13,14 As informações ósseas descritas por DXA incluíram densidade mineral óssea total e da coluna (DMO, g/cm²), conteúdo mineral ósseo (CMO, g) e área óssea (cm²).…”

Section: Métodosunclassified

Taro (Colocasia esculenta) flour intake enable bone integrity in male rats

Pessoa¹,

Abreu

Gracio

et al. 2021

DEMETRA

View full text Add to dashboard Cite

Objetivo: A proposta deste estudo foi investigar a composição óssea em ratos tratados com dieta suplementada com farinha de taro (Colocasia esculenta) até eles completarem 90 dias de idade. Métodos: No momento do desmame, os ratos foram divididos em grupo controle (C, n = 11) e experimental (T, n = 12) – composto por animais tratados com farinha de taro até os 90 dias de idade. Ingestão alimentar, massa e comprimento corporal foram avaliados semanalmente ao longo de todo o período experimental. Dimensões ósseas, bem como a densidade mineral óssea (DMO), conteúdo mineral ósseo (CMO), área óssea total e propriedades biomecânicas foram determinadas no final de 90 dias. Resultados: Grupo T apresentou elevados valores (P<0.05) para massa e comprimento corporal; DMO, CMO e área óssea da coluna vertebral; DMO na quarta vértebra lombar; massa femoral, distância entre as epífises, largura do ponto médio da diáfise, DMO, força máxima e concentrações séricas de osteocalcina, quando comparado ao grupo controle. Conclusões: A ingestão da farinha de taro apresentou efeito positivo na saúde óssea.

show abstract

Beneficial effects of flaxseed polysaccharides on metabolic syndrome via gut microbiota in high-fat diet fed mice

Yang

Deng

et al. 2020

Food Research International

View full text Add to dashboard Cite

Body composition in male rats subjected to early weaning and treated with diet containing flour or flaxseed oil after 21 days until 60 days

Cited by 10 publications

References 21 publications

Early weaning alters redox status in the hippocampus and hypothalamus of rat pups

Early weaning alters redox status in the hippocampus and hypothalamus of rat pups

Taro (Colocasia esculenta) flour intake enable bone integrity in male rats

Beneficial effects of flaxseed polysaccharides on metabolic syndrome via gut microbiota in high-fat diet fed mice

Contact Info

Product

Resources

About