BMSCs-derived exosome miR-29a-3p improved the stability of rat myasthenia gravis by regulating Treg/Th17 cells
Zhongben Tang,
Meiqiu Chen,
Chen Chen
et al.
Abstract:Myasthenia gravis (MG) is an autoimmune disorder mediated by antibodies targeting the acetylcholine receptor. Exosomal-derived miRNAs have been implicated in immune modulation and the pathogenesis of autoimmune diseases. However, the expression and functional role of exosomal miR-29a-3p in MG remains poorly understood. This study aimed to investigate the therapeutic effect and mechanism of miR-29a-3p derived from stem cell exosomes (Exos) on experimental autoimmune myasthenia gravis (EAMG) rats. EAMG was induc… Show more
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