BMI and All-Cause Mortality in Normoglycemia, Impaired Fasting Glucose, Newly Diagnosed Diabetes, and Prevalent Diabetes: A Cohort Study

Abstract

U-curve relationships existed regardless of diabetes status. Optimal BMI for lowest mortality became gradually higher with worsening diabetes for each sex and each age-group.

Body mass index and risk of all-cause mortality with normoglycemia, impaired fasting glucose and prevalent diabetes: results from the Rural Chinese Cohort Study

“…However, this study had inadequate statistical power because it included only 507 patients with diabetes 26. The Korean Metabolic Risk Factor Study observed a U-curved relation between BMI and 10-year all-cause mortality regardless of diabetes status 27. Among 12 million Korean adults, the optimal BMI for the lowest mortality increased with worsening diabetes for both sexes.…”

“…Information on the BMI–mortality association among Asian patients with diabetes (Japan,26 Korea27 and China28–30) is limited. The Jichi Medical School Cohort Study reported a high risk of 10-year all-cause mortality for Japanese patients with diabetes with leanness (BMI 14.2–21.1 kg/m 2 ) regardless of age.…”

Body mass index and the risk of acute pancreatitis by etiology: A prospective analysis of Korean National Screening Cohort

“…Second, the inaccuracy of self‐reported BMI measurements may be partially responsible. Third, the older age of the participants may have also contributed to the weak associations in some studies, because the associations of BMI are generally weaker at older ages …”

Risk factors for hepatocellular carcinoma by age, sex, and liver disorder status: A prospective cohort study in Korea

“…ALT and AST were measured using the nicotinamide adenine dinucleotide‐ultraviolet (NADH‐UV) absorption method or the Reitman‐Frankel method. Fasting serum glucose was assayed using enzymatic methods . Blood pressure was measured using a standard mercury sphygmomanometer.…”

“…In the current prospective cohort study, we identified HCC incidence according to risk factors. We then examined the associations between potential risk factors and HCC and studied whether the associations differed by age, sex, or liver disorder status …”