BLV-CoCoMo-qPCR: estimation of bovine leukemia virus (BLV) proviral load harbored by lymphocyte subpopulations in BLV-infected cattle at the subclinical stage of enzootic bovine leucosis

Conference Highlights of the 16th International Conference on Human Retrovirology: HTLV and Related Retroviruses, 26–30 June 2013, Montreal, Canada

“…They observed that a mutation that blocks glycosylation at residue N230 enhances, rather than inhibits, replication of the virus in vivo . Novel insights into the infected lymphocyte populations in BLV-infected, clinically normal cattle were provided by Aida et al ., who developed a quantitative real-time PCR method that measures the PVL of both known and novel BLV variants in infected animals, like that in HTLV-1-associated ATLL [ 189 ]. They observed that PVL correlates with BLV disease progression.…”