Blurred Vision Caused by Inflammation of the Optic Nerves Due to a Pituitary Abscess-Case Report-

Utsuki, Satoshi; Oka, Hiroyuki; Tanaka, Satoshi; Iwamoto, Kazuhisa; Hasegawa, Hitomi; Hirose, Ryuichi; Fujii, Kiyotaka

doi:10.2176/nmc.45.327

Cited by 10 publications

(4 citation statements)

References 17 publications

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“…Vates et al reported 24 cases drawn from a series of more than 3500 patients who underwent pituitary surgery [2]. [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22], and a summary of these cases, which we selected for analysis, has been tabulated in Table 2, 3 and 4.…”

Section: Discussionmentioning

confidence: 99%

Pituitary abscess: our experience with a case and a review of the literature

Dalan

Leow

2007

Pituitary

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Pituitary abscess is a rare disease. Due to its potentially high mortality and morbidity rate, it should be considered in the differential diagnosis of sellar masses. Despite recent advances in radiological investigations, making a definitive diagnosis preoperatively remains challenging. This 45-year-old Indian gentleman presented with severe throbbing headache for six months. Magnetic resonance imaging of the brain revealed a sellar mass with peripheral enhancement that was misdiagnosed as a pituitary macroadenoma. A trans-sphenoidal excision was done, which surprisingly yielded only pus that was drained accordingly from the lesion. Fungal and bacterial cultures were negative. However this patient subsequently lost complete function of the pituitary gland, resulting in central diabetes insipidus and required permanent hormonal replacement therapy in the deficient endocrine axes. A Medline search was conducted and a review of 24 cases reported in the last 5 years discussed.

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Section: Discussionmentioning

confidence: 99%

Pituitary abscess: our experience with a case and a review of the literature

Dalan

Leow

2007

Pituitary

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“…The presence of a round cystic mass with a thin peripheral rim enhancement following gadolinium injection at MRI, occasionally associated with a thickened pituitary stalk and symptoms of diabetes insipidus may be suggestive of pituitary abscess. Based on the MRI image, differential diagnosis of the sellar mass with other diseases such as a pituitary adenoma [2,7,32], pituitary apoplexy [33], pituitary germinal tumor [34] or hypophysitis [3] is to be considered. Diabetes insipidus has been reported only in some cases, but pituitary insufficiency and symptoms of intracranial mass are common; in few cases, pituitary insufficiency may not develop as shown by Takahashi in a 13-years-old girl with pituitary abscess associated to mild sphenoid sinusitis [7].…”

Section: Discussionmentioning

confidence: 99%

Primary pituitary abscess followed by empty sella syndrome in an adolescent girl

Pepene¹,

Ilie²,

Mihu³

et al. 2008

Pituitary

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Primary pituitary abscess is a rare pituitary pathology, particularly at a young age and is characterized by atypical clinical features making the diagnosis difficult. Correct diagnosis and therapy are mandatory due to the potentially lethal outcome of pituitary infection. We report the case of an adolescent girl presenting with headache, diabetes insipidus and central thyro-gonadic insufficiency with no history of infection, in whom the intra-operative diagnosis of primary pituitary abscess was made. Bacterial cultures indicated infection with Streptococcus spp. One year after neurosurgery and antibiotic therapy, recovery of diabetes insipidus and pituitary insufficiency was documented except for persistence of subnormal growth hormone secretion. Post-surgery, pituitary magnetic resonance imaging revealed an empty sella syndrome.

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“…Pituitary abscess is a very rare condition, comprising only around 0.3 % of pituitary tumours and less than 1 % of all pituitary diseases ( Domingue, Wilson 1977 ;Vates et al, 2001 ; Bakker and Hoving, 2010 ). Symptoms are similar to other pituitary tumours including headache, visual fi eld defects and problems associated with pituitary hormone defi ciency ( Utsuki et al, 2005 ;Carpinteri et al, 2009 ). Diabetes insipidus is one of the most common features and may be helpful for diff erential diagnosis as it is rarely a characteristic symptom of pituitary adenomas ( Fuyi et al, 2010 ).…”

Section: Introduction ▼mentioning

confidence: 99%