Bluetongue virus in South America, Central America and the Caribbean

Legisa, Danilo Mario; Gonzalez, F.N.; Santos, María José Dus

doi:10.1016/j.virusres.2013.10.030

Cited by 34 publications

(35 citation statements)

References 42 publications

(65 reference statements)

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“…BTV-10, 12, 14, 13, 17 and 24 had been previously identified in South America (Homan et al, 1985;Lancelot et al, 1989). More recently BTV-4 was isolated in Argentina and Brazil (Legisa et al, 2013(Legisa et al, , 2014.…”

Section: Discussionmentioning

confidence: 99%

Identification of bluetongue virus and epizootic hemorrhagic disease virus serotypes in French Guiana in 2011 and 2012

Viarouge

Lancelot

Rives

et al. 2014

Veterinary Microbiology

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Section: Discussionmentioning

confidence: 99%

Identification of bluetongue virus and epizootic hemorrhagic disease virus serotypes in French Guiana in 2011 and 2012

Viarouge

Lancelot

Rives

et al. 2014

Veterinary Microbiology

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“…9 In South America, Central America, and the Caribbean, serotypes 1,3,4,6,8,11,12,14, and 17 have been detected by serotype-specific antibodies, and serotypes 1,3,4,6,8,12, and 17 have been detected by virus isolation. 6 In the United States, serotypes 1-3, 5, 6, 9-14, 17, 19, 22, and 24 have been identified. 11 Furthermore, the clinical presentation of bluetongue is a very rarely reported condition.…”

mentioning

confidence: 99%

Outbreak of Bluetongue virus serotype 4 in dairy sheep in Rio de Janeiro, Brazil

et al. 2014

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Abstract. In late January 2013, 10 nonpregnant Lacaune dairy ewes raised under extensive husbandry management on a farm in Rio de Janeiro, Brazil, presented with the general clinical signs of lethargy, hyporexia, edema of the face, hyperemia of the exposed parts of the skin, mouth lesions, pyrexia, and lameness. Additionally, 2 pregnant ewes died suddenly after the onset of respiratory signs. The complete blood counts and biochemistry analyses showed neutrophilic leukocytosis with monocytosis and reactive lymphocytes, normocytic normochromic anemia and increased aspartate aminotransferase levels. Postmortem examination revealed erosions on the lingual mucosa, bilateral submandibular ganglia infarctions, yellow foamy fluid accumulation in the trachea and bronchial bifurcation, pulmonary congestion, and edema associated with hemorrhagic lesions on the pulmonary artery and heart. The clinical and pathological findings were suggestive of bluetongue. For a molecular and virological diagnosis, tissue samples were analyzed by Bluetongue virus-specific real-time reverse transcription polymerase chain reaction (qRT-PCR), and viral isolation was performed in embryonated chicken eggs. For viral typing, positive tissue and egg-isolated samples were analyzed by qRT-PCR using primers and probes specific for the structural VP2 gene in genome segment 2 of all 26 serotypes. There are still no contingency plans for responding to an outbreak of bluetongue disease in Brazil, and this episode emphasizes the need for continuing serological and entomological surveillance programs. Additionally, this report describes the isolation of Bluetongue virus serotype 4 in sheep in the Americas.

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“…BTV serotype 4 (BTV4) strain used in this study was an Argentine isolated named 4/ARG/829/2001, described by Legisa [25,26]. Segment 2 (Seg2) open reading frame was cloned into pFastBacDual plasmid (Invitrogen).…”

Section: Construction Of Recombinant Baculovirusesmentioning

confidence: 99%

An experimental subunit vaccine based on Bluetongue virus 4 VP2 protein fused to an antigen-presenting cells single chain antibody elicits cellular and humoral immune responses in cattle, guinea pigs and IFNAR(−/−) mice

Legisa¹,

Aguirreburualde²,

Gonzalez³

et al. 2015

Vaccine

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Bluetongue virus in South America, Central America and the Caribbean

Cited by 34 publications

References 42 publications

Identification of bluetongue virus and epizootic hemorrhagic disease virus serotypes in French Guiana in 2011 and 2012

Identification of bluetongue virus and epizootic hemorrhagic disease virus serotypes in French Guiana in 2011 and 2012

Outbreak of Bluetongue virus serotype 4 in dairy sheep in Rio de Janeiro, Brazil

An experimental subunit vaccine based on Bluetongue virus 4 VP2 protein fused to an antigen-presenting cells single chain antibody elicits cellular and humoral immune responses in cattle, guinea pigs and IFNAR(−/−) mice

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