Blue-yellow deficiency in workers exposed to low concentrations of organic solvents

Muttray, Axel; Wolff, Udo; Jung, Detlev; Konietzko, J

doi:10.1007/s004200050237

Cited by 42 publications

(24 citation statements)

References 28 publications

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“…Since subjects with such diseases were excluded from the present study, medical reasons might not be significant for the observed changes in colour preferences with ageing. Likewise, occupational reasons, e.g., the exposure to organic solvents that might account for acquired colour vision defects [29], are not important for the present results, as the respective subjects were excluded from this study. Therefore, the main explanations for the present results may rely upon psychological and biological changes during the course of ageing.…”

Section: Age Differences In Colour Preferencesmentioning

confidence: 94%

Changing Colour Preferences with Ageing: A Comparative Study on Younger and Older Native Germans Aged 19–90 Years

Dittmar¹

2001

Gerontology

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Background: Previous studies have shown that colour preferences change from early childhood to adulthood. Objective: The main objective of this study was to assess whether colour preferences undergo further changes during adult life. Methods: Cross-sectional data on colour preferences were collected in 842 adults (aged 19–90 years) living in Mainz, Germany. The sample was split by age into younger (183 men, 232 women) and older (157 men, 270 women) adults. The subgroups were compared for their most and least preferred colours that they had chosen by name out of four given colours (blue, green, red, yellow). Differences in the pattern of frequencies between sexes and age groups were assessed for statistical significance using chi-square analyses. Results: Both age groups and both sexes chose blue as most preferred colour and yellow as least preferred one; green and red fluctuated in the middle position of the rank order of preferences. All frequency distributions departed significantly from chance (p < 0.001). In both younger and older adults, significant sex differences did not exist for the ranking of the most preferred colours (p > 0.2), but were evident in the ranking of the least preferred colours (p < 0.01); men stated more often yellow and less often red as least preferred than women did. Age group differences in colour preferences were highly significant. With advancing age, the preference for blue decreased steadily, whereas the popularity of green and red increased (p < 0.001). Conclusions: The results suggest that colour preferences change during the course of the adult life span. These changes seem to be a reversal of the trend reported in the literature for children. Changed colour preferences in the aged might be attributed to alterations in colour discrimination and visual imagery, the yellowing of the crystalline lens, and the decreased function of the blue cone mechanism with ageing.

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Section: Age Differences In Colour Preferencesmentioning

confidence: 94%

Changing Colour Preferences with Ageing: A Comparative Study on Younger and Older Native Germans Aged 19–90 Years

Dittmar¹

2001

Gerontology

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“…Emerging evidence suggests that occupational exposure to organic solvents may be associated with impairment of visual function in many respects, and in particular color vision, including losses of blue yellow color, and secondary red green color dyschromatopsia [185][186][187].…”

Section: Ocular Effectsmentioning

confidence: 99%

Recent advances in occupational and environmental health hazards of workers exposed to gasoline compounds

Ekpenyong

Asuquo

2017

Int J Occup Med Environ Health

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The impact of health and environmental hazards, associated with the constituents of gasoline, on occupationally exposed workers has been recorded over the past few decades. However, the scientific literature on their pathogenic potential remains incomplete, which could affect the current understanding of the associated health risks. This review provides current information based on recently improved research techniques to evaluate gasoline toxicity profiles for humans. Our current knowledge provides insight into the intricate mechanism of gasoline-induced adverse effects, including the formation of reactive metabolites via bio-activation and subsequent generation of reactive oxygen species (ROS) and oxidative stress, which are involved in multiple mechanisms that are central to the aetiology of gasoline-induced toxicity. These mechanisms include covalent binding to deoxyribonucleic acid (DNA), leading to oxidative damage, tumor-suppression gene activity, and activation of pro-oncogenes. Furthermore, it results in induction of autoimmunity and local inflammatory responses, disruption of multiple neurotransmitters and immune cell function, derangement of various enzyme activities (e.g., sodiumpotassium adenosine triphosphate (Na + /K + /ATPase) activity, cytochrome P450 (CYP450), nitric oxide synthase (NOS), antioxidant enzyme activities, etc.), conjugation of bile, and non-specific cell membrane interaction, leading to damage of the membrane lipid bilayer and proteins. Available data suggests that exposure to gasoline or gasoline constituents have the potential to cause different types of illnesses. The data highlights the need to maintain safety measures via suitable research, medical surveillance, regulatory control, life style modification, early detection, and intervention to minimize exposure and manage suspected cases. They also present novel opportunities to design and develop effective therapeutic strategies against gasoline-induced detrimental effects. Int J Occup Med Environ Health 2017;30(1):1-26

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“…Muttray et al 4) examined 24 workers exposed to mixtures of solvents and 24 controls. They found a significantly lower CCI (median: 1.0) in exposed than in controls (1.17).…”

Section: Color Vision Dysfunction In Solvent-exposed Paintersmentioning

confidence: 99%

“…They are not relevant from a clinical point of view. Muttray et al 4) showed that CCI values of this magnitude do not restrict the suitability of workers, even in occupations such as printing, in which good color vision is usually necessary. Solvent induced color vision dysfunction is to a great extent or even completely reversible after exposure stops as was shown in the case of tetrachlorethylene and styrene 3,15) .…”

Section: Color Vision Dysfunction In Solvent-exposed Paintersmentioning

confidence: 99%

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Pilot Study on Prevalence of Color Vision Dysfunction in Long-Term Solvent-Exposed Painters.

et al. 2003

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Blue-yellow deficiency in workers exposed to low concentrations of organic solvents

Abstract: This study gives further evidence that even mixtures of organic solvents at concentrations below the threshold-limit values may impair color vision.

Cited by 42 publications

References 28 publications

Changing Colour Preferences with Ageing: A Comparative Study on Younger and Older Native Germans Aged 19–90 Years

Changing Colour Preferences with Ageing: A Comparative Study on Younger and Older Native Germans Aged 19–90 Years

Recent advances in occupational and environmental health hazards of workers exposed to gasoline compounds

Pilot Study on Prevalence of Color Vision Dysfunction in Long-Term Solvent-Exposed Painters.

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