Blue Nevus of the Hard Palate: The Importance of a Careful Examination in an Emergency Setting

Tavares, Alcina; Pereira, André; Pimentel, João; Prates, Marcelo; Fonseca, Lino; Marques, Maria Rosário; Proença, Francisco

doi:10.1155/2022/6329334

Cited by 2 publications

(7 citation statements)

References 21 publications

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“…Malignant transformation or recurrence of blue nevus, though extremely rare, can be, in fact, develop [2,11]. Indeed, oral nevi and oral malignant melanomas have several similarities.…”

Section: Discussionmentioning

confidence: 99%

“…Oral melanocytic nevi (OMNs) are rare and benign melanocytic tumors [2,5,7,11]. Long associated with hamartomas, melanocytic nevi are now considered as neoplasms [7].…”

Section: Introductionmentioning

confidence: 99%

“…They are classified histologically as junctional, compound, intradermal, combined and blue. This classification is correlated with the location, morphology of the cells and their distribution [2,7]. By definition, melanocytes are located in the basal layer of the epithelium, originating from the neural crest and are present in the skin and mucous membranes [2,9,11].…”

Section: Introductionmentioning

confidence: 99%

“…This classification is correlated with the location, morphology of the cells and their distribution [2,7]. By definition, melanocytes are located in the basal layer of the epithelium, originating from the neural crest and are present in the skin and mucous membranes [2,9,11]. They are very often embedded between the basal keratinocytes.…”

Section: Introductionmentioning

confidence: 99%

“…Women tend to be more commonly affected than men with a higher frequency between the 3rd and the 5th decade of life [2,5,6,10,11].…”

Section: Introductionmentioning

confidence: 99%

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Blue Nevus: A Case Report

Camille¹

2022

IJCIMR

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Oral melanocytic nevi are rare and benign tumors arising from melanocytes located in the oral mucosa. These lesions are clinically asymptomatic and often discovered during a dental consultation . All melanocytic proliferations are not benign and an histological examination have to be performed to rule out malignancy and adjust the treatment and the follow-up. Herein, we presented the case of a 23-year-old-Asian woman with an asymptomatic pigmented lesion on the hard palate discovered during a dental consultation. The lesion was excised and sent to the anatomopathological laboratory and turned out to be a blue nevus, a particular subtype of nevus.

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“…Malignant transformation or recurrence of blue nevus, though extremely rare, can be, in fact, develop [2,11]. Indeed, oral nevi and oral malignant melanomas have several similarities.…”

Section: Discussionmentioning

confidence: 99%

“…Oral melanocytic nevi (OMNs) are rare and benign melanocytic tumors [2,5,7,11]. Long associated with hamartomas, melanocytic nevi are now considered as neoplasms [7].…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…Women tend to be more commonly affected than men with a higher frequency between the 3rd and the 5th decade of life [2,5,6,10,11].…”

Section: Introductionmentioning

confidence: 99%

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Blue Nevus: A Case Report

Camille¹

2022

IJCIMR

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A Case Series on Intraoral Blue Nevi with a Literature Review-Based Clinico-Pathologic Comparison of Intraoral Blue Nevi with Other Oral Melanocytic Nevi

2023

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Nevi are pigmented lesions of bluish-black colour that may occasionally occur in the oral cavity. Out of several oral melanocytic nevi (OMN), blue nevi are significant as some variants are diagnostically challenging due to histopathological overlap with malignant melanoma. The aim of the present report was to present the clinico-pathologic characteristics of 8 new cases of intraoral common blue nevi and 22 OMN. A literature review-based comparison of the clinico-pathological characteristics of intraoral blue nevi with intramucosal nevi is presented. Analysis of the clinico-pathologic characteristics of eight common blue nevi revealed that they are generally small lesions of less than 1 cm in size and are of bluish-black colouration. These lesions were commonly identified in adults (88%), with a female predilection. The hard palate was the most common site of occurrence. These findings could be collaborated with the findings observed in the literature review. It was also revealed that a common blue nevus was the second most common lesion among all OMN. The intraoral common blue nevi included in the present series did not show recurrences or undergo malignant transformation after being followed up for up to 15 years. Unlike a common blue nevus, the literature reveals that a cellular blue nevus or its atypical variant is more diagnostically challenging, while a diagnosis of an epithelioid blue nevus should be followed up with investigations to exclude Carney complex. In conclusion, this case series and literature review reveal that OMN, including intraoral common blue nevi, are small indolent lesions with extremely low malignant transformation potential. A significantly smaller size, well-defined margins and lack of variegations in colour are all features that could be used as clues to differentiate intraoral common blue nevi from mucosal malignant melanoma. However, the diagnosis needs to be confirmed with histopathology.

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Blue Nevus of the Hard Palate: The Importance of a Careful Examination in an Emergency Setting

Cited by 2 publications

References 21 publications

Blue Nevus: A Case Report

Blue Nevus: A Case Report

A Case Series on Intraoral Blue Nevi with a Literature Review-Based Clinico-Pathologic Comparison of Intraoral Blue Nevi with Other Oral Melanocytic Nevi

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