Blue Light Protecting Cosmetic Active Ingredients: A Case Report

Abstract

Background: High energy visible lights more and more attracts notice in the cosmetic science field. It is well known that UV light harms skin cells and unprotected exposure to this harmful radiation leads to premature skin ageing. Recently, the impact of blue light on human skin is investigated in-vitro and in-vivo. Evidence grows that blue light increases reactive oxygen species (ROS) intracellular which leads to cell damage and subsequent apoptosis. Methods:HaCaT cells were cultivated and incubated with anti-oxidative cosmetic active ingredients. After irradiation of the cells with defined blue light, the intracellular ROS were detected by fluorescent staining and cell sorting. The effect of one cosmetic active ingredient was determined in an application study for three months, visualization of rosacea teleangiectoides and quantification of red spots was done with a VISIA-CR photographic system. Results:All investigated cosmetic active ingredients exhibited ROS reduction close to the baseline level after 2 hours of blue light irradiation. Application of one cosmetic active ingredient to the facial skin revealed a statistically significant reduction in red spots count and a markedly reduction of rosacea teleangiectoides by 44.3 % in one test subject. Conclusion:Anti-oxidant cosmetic active ingredients are capable of protecting skin cells from the impact of blue light and lead to a visible reduction of ROS induced skin aberrations in vivo.