BLSD experimental course for blind people

Ciapetti, Marco; Terrosi, L.; Morellato, C.; Lumini, Enrico; Senes, G.; Chiti, M.; Ferrara, Angelo; Calzolari, P.; Rossinelli, R.; Dini, S; Peris, A.

doi:10.1016/j.resuscitation.2009.10.010

Cited by 1 publication

(2 citation statements)

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“…However, SpO 2 >95% occurred in the majority of infants, especially in the infants who received PPV, which probably reflects the difficulty of simultaneously performing PPV and titrating oxygen. These observations suggest that targeting a higher percentile as currently recommended in international guidelines [7], [8] (25 th –50 th percentile) might improve respiratory drive. A more stepwise increase in FiO 2 and more diligence in reducing FiO 2 , for example when SpO 2 >85%, could reduce the risk of hyperoxia.…”

Section: Discussionmentioning

confidence: 82%

“…Meta-analyses indicate that resuscitation of term infants at birth with air significantly reduced mortality compared with those resuscitated with fraction of inspired oxygen (FiO 2 ) of 1.0 [1]–[6]. International resuscitation guidelines now recommend term infants should start in air [2], [7], [8]. Less clinical data are available for preterm infants, but guidelines now recommend to use oxygen judiciously during stabilization of preterm infants at birth [2], [7]–[9].…”

Section: Introductionmentioning

confidence: 99%

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The Administration of 100% Oxygen and Respiratory Drive in Very Preterm Infants at Birth

et al. 2013

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AimTo retrospectively investigate the changes of SpO2 and respiratory drive in preterm infants at birth after administration of 100% oxygen.MethodsRespiratory parameters, FiO2 and oximetry of infants <32 weeks gestation before and after receiving FiO2 1.0 were reviewed during continuous positive airway pressure (CPAP) or positive pressure ventilation (PPV).ResultsResults are given as median (IQR) or percentages where appropriate. Suitable recordings were made in 50 infants (GA 27 (26–29) weeks), 17 received CPAP and 33 PPV. SpO2 increased rapidly in the first minute after FiO2 1.0 and remained stable. The duration of FiO2 1.0 tended to be shorter in the CPAP group than in the PPV group (CPAP vs. PPV: 65 (33–105) vs. 100 (40–280) s; p = 0.05), SpO2 >95% occurred more often in PPV group (53% vs. 69%) and lasted longer (70(40–95) vs. 120(50–202) s). In CPAP group, minute volume increased from 134 (76–265) mL/kg/min 1 minute before to 240 (157–370) mL/kg/min (p<0.01) 1 minute after start FiO2 1.0 and remained stable at 2 minutes (252 (135–376) mL/kg/min; ns). The rate of rise to maximum tidal volume increased (from 13.8 (8.0–22.4) mL/kg/s to 18.2 (11.0–27.5) mL/kg/s; p<0.0001) to 18.8 (11.8–27.8) mL/kg/s; ns). In the PPV group respiratory rate increased from 0(0–4) to 9(0–20) at 1 minute (p<0.001) to 23 (0–34) breaths per minute at 2 minutes (p<0.01).ConclusionIn preterm infants at birth, a rapid increase in oxygenation, resulting from a transient increase to 100% oxygen might improve respiratory drive, but increases the risk for hyperoxia.

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Section: Discussionmentioning

confidence: 82%