Bloody nipple discharge in infancy—report of two cases: Figure 1

Abstract

SummaryBloody nipple discharge (BND) in infancy is an exceptionally rare finding. We report the cases of two children who are 9 and 29 months old. The first case presented with 1 month of bilateral intermittent blood-stained nipple discharge with no other symptoms. The second case presented with 15 days of intermittent right BND and a small palpable mass, without obvious signs of inflammation. The coagulation and hormonal tests were within the age-appropriate reference ranges. Ultrasound examination was normal. Cytological evaluation of nipple discharge showed no malignant cells. Both patients had spontaneous symptoms resolution. BND in paediatric age is usually benign and self-limited and often related to mammary duct ectasia. Unnecessary invasive procedures or treatments should be avoided. BACKGROUND

Cytological Evaluation of Pathological Male Breast Lesions

“…Most cases resolve spontaneously within 6-9 months. Excision should be avoided, as it may cause permanent mammary deformity or dysfunction since an early age (23). Quite differently, in the presented infant, his nipple discharge subsided within 4 months of follow-up.…”

Mammary duct ectasia without bloody nipple discharge in a five‐year‐old girl

“…Treatment of pediatric duct ectasia can be expectant. Data reported in the literature demonstrate that MDE may be considered a self‐limiting condition, solving spontaneously in 6/9 months, even when BND is present, especially in infants 4 . Conversely, in children, the MDE may persist displaying often non‐specific ultrasound patterns without signs of BND.…”

“…3 The finding of dilated ducts is common but not constant and should be correlated with reported symptoms. The commonest clinical presentation is BND, 4 reported in 27 patients (77%). In the great part of cases, BND is reported in infants.…”