Bloody nipple discharge as a benign, self-limiting disorder in young children: A systematic review including two related case reports

Ultrasound Findings of Mammary Duct Ectasia Causing Bloody Nipple Discharge in Infancy and Childhood

“…Bilateral involvement can be synchronous or metachronous. To the best of our knowledge, only 8 cases of bilateral mammary duct ectasia in infants and children were identified in the literature . In our series, 2 cases had bilateral disease.…”

“Coffee‐colored” nipple discharge in prepubertal age

“…Furthermore, a diagnosis and treatment algorithm for children presenting a bloody nipple discharge has been developed not so long ago 4 . Particularly, first‐line conservative management is usually recommended especially in girls, and surgery is mandatory only in selected cases 2,4,5 . In the present case, despite rarity of a “coffee‐colored” nipple discharge, the young patient was successfully treated via conservative therapy as recommended by the scientific community without the necessity to perform a biopsy and/or a surgical approach.…”

“…Although BND can be associated with breast malignancy in adults, all of the cases reported in the literature about pediatric patients presenting bloody nipple discharge have been associated with benign pathologies. Notably, the most frequent benign pathology described in these children is mammary ductal ectasia 1,2 …”

Bloody Nipple Discharge in Infants

“…Bloody nipple discharge often occurs in children under 4 years of age. While there is a male predominance in an under-aged child, both genders are seen at equal frequency in children over 1 year (8). Mendez-Gallart et al, reported a 9 years old male patient with ductal ectasia and a persistent palpable breast mass (3).…”