Bloodstream Infections Among Transplant Recipients: Results of a Nationwide Surveillance in Spain1

Moreno, Asunción; Cervera, Carlos; Gavaldá, Joan; Rovira, Montserrat; Cámara, Rafael de la; Jarque, Isidro; Montejo, Miguel; Torre‐Cisneros, Julián; Cisneros, José Miguel; Fortün, Jesús; López‐Medrano, Francisco; Gurguí, M.; Muñóz, Patricia; Ramos, António; Carratalà, Jordi

doi:10.1111/j.1600-6143.2007.01964.x

Cited by 201 publications

(220 citation statements)

References 23 publications

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“…Linares et al (3) also yielded the same significance within 30 days posttransplantation. The incidence was higher among all types of SOT compared to the study performed by Moreno et al (9) (9). BSI among heart transplant recipients was published less often in the literature compared to BSI among other SOT types.…”

Section: Discussioncontrasting

confidence: 51%

Bloodstream Infections among Solid Organ Transplant Recipients: Eight Years’ Experience from a Turkish University Hospital

Yeşilkaya¹,

Azap²,

Demirkaya³

et al. 2013

Balkan Med J

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Background: Bloodstream infections (BSI) are frequently seen after solid organ transplantation. The incidence of bloodstream infections differs among the types of transplantation. The microbiological features and antimicrobial resistance patterns change from centre to centre. Aims: To evaluate the incidence and spectrum of aetiological agents of bloodstream infections among solid organ transplantation recipients.Study Design: Retrospective descriptive study.Methods: Medical records of solid organ transplant recipients in the period between January 1 st 2004 and August 15 th 2012 were assessed retrospectively. The study population comprised 927 (64 heart, 556 kidney, 307 liver) consecutive recipients. Bloodstream infections were divided into three groups according to the onset time of bloodstream infections after transplantation: early, mid-term and late. The incidence and microbiological features of bloodstream infections were evaluated.Results: The number of bloodstream infection episodes was 317 in 191 recipients which was distributed as 228 (72%) in liver, 70 (22%) in kidney and 19 (6%) in heart transplantation. Ninety-eight 98 (30.9%) of the episodes were diagnosed within the early period, 134 (42.3%) within the mid-term and 85 (26.8%) in the late period. Early and mid-term bloodstream infections were seen statistically more often in liver than in kidney or heart transplantation (p=0.01 and p=0.031, respectively). Late bloodstream infections were also common in liver transplant recipients which was not statistically significant (p=0.229).Conclusion: Liver transplant recipients are at the highest risk for developing BSI after transplantation in early, mid-term and late periods.

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Section: Discussioncontrasting

confidence: 51%

Bloodstream Infections among Solid Organ Transplant Recipients: Eight Years’ Experience from a Turkish University Hospital

Yeşilkaya¹,

Azap²,

Demirkaya³

et al. 2013

Balkan Med J

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“…Bacterial infections are more prevalent when the etiologic distribution of postoperative infections is concerned. These infections are usually observed in the surgical site, the abdomen, the urinary tract, the respiratory tract, and at the site of the catheter (1).…”

mentioning

confidence: 99%

Prognostic Value of Procalcitonin, CRP, Serum Amyloid A, Lactate and IL-6 Markers in Liver Transplant Patients Admitted to ED with Suspected Infection

Gür¹,

Oğuztürk

Kose

et al. 2017

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“…62 Among solid organ transplant recipients, candidemia compared to the Gram-positive and Gram-negative bloodstream infections was associated with a higher crude mortality. 4 Nosocomial transmission of Candida spp. from health care workers to patients has been documented and also implicated in outbreaks.…”

Section: Antimicrobial Stewardship Programsmentioning

confidence: 99%

“…Infections have been recognized as a frequent complication with bacterial pathogens playing a major role in the immediate postoperative period followed by viral and fungal organisms. [1][2][3][4][5] Among fungal infections, Candida spp. and Aspergillus spp.…”

Section: Introductionmentioning

confidence: 99%

Management of Candida infections in liver transplant recipients: current perspectives

Lingegowda¹,

Tan²

2014

TRRM

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Liver transplantation has emerged as a widely accepted lifesaving therapeutic option for many patients with a variety of liver diseases. Improved surgical and medical management has led to significant improvements in post-transplant survival rates with a 1 year and 5 year patient survival of 87% and 73%, respectively. A high mortality rate due to infections during the first post-transplant year persists. Invasive candidiasis is recognized as a significant problem associated with high morbidity and mortality. Recent surveillance data has helped to understand the changes in the epidemiology and the evolving trends in the use of antifungal agents for prophylaxis and treatment combined with the challenges of managing these invasive fungal infections, which has led the transplant community to explore the best management strategies. The emergence of resistant fungi and excess costs in managing these invasive fungal infections has added to the complexities of management. In this context, current perspectives in the management of Candida infections in liver transplant recipients will be reviewed.

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Bloodstream Infections Among Transplant Recipients: Results of a Nationwide Surveillance in Spain1

Cited by 201 publications

References 23 publications

Bloodstream Infections among Solid Organ Transplant Recipients: Eight Years’ Experience from a Turkish University Hospital

Bloodstream Infections among Solid Organ Transplant Recipients: Eight Years’ Experience from a Turkish University Hospital

Prognostic Value of Procalcitonin, CRP, Serum Amyloid A, Lactate and IL-6 Markers in Liver Transplant Patients Admitted to ED with Suspected Infection

Management of Candida infections in liver transplant recipients: current perspectives

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