2021
DOI: 10.21037/tlcr-20-933
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Abstract: Background: Despite common use in clinical practice, the impact of blood transfusions on prognosis among patients with lung cancer remains unclear. The purpose of the current study is to perform an updated systematic review and meta-analysis to evaluate the influence of blood transfusions on survival outcomes of lung cancer patients.Methods: We searched PubMed, Embase, Cochrane Library, and Ovid MEDLINE for publications illustrating the association between blood transfusions and prognosis among people with lun… Show more

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Cited by 6 publications
(2 citation statements)
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“…In addition, preoperative anaemia has been associated with an increased incidence of receiving perioperative transfusions, which is also linked to increased postoperative morbidity and mortality [2]. Cho et al [10] showed that blood transfusions in patients with lung cancer decreases overall survival and disease-free survival in a large meta-analysis of 12 175 patients that included perioperative transfusion data. Worse overall survival, disease-free survival and recurrence were noted in a dose-dependent relationship with increasing units of blood transfusions above a single unit in a study by Jawad Latif et al [11].…”
Section: Why Anaemia Is Harmfulmentioning
confidence: 99%
“…In addition, preoperative anaemia has been associated with an increased incidence of receiving perioperative transfusions, which is also linked to increased postoperative morbidity and mortality [2]. Cho et al [10] showed that blood transfusions in patients with lung cancer decreases overall survival and disease-free survival in a large meta-analysis of 12 175 patients that included perioperative transfusion data. Worse overall survival, disease-free survival and recurrence were noted in a dose-dependent relationship with increasing units of blood transfusions above a single unit in a study by Jawad Latif et al [11].…”
Section: Why Anaemia Is Harmfulmentioning
confidence: 99%
“…While postoperative bleeding occurs rarely in primary lung tumor surgery (1.3–2.1%) [ 1 , 2 ], ABT occurs in 9–55.4% of patients [ 3 , 4 ]. ABT carries a risk for complications, negatively impacts prognosis [ 5 ] and is limited by the availability of red blood cell (RBC) units. Therefore, preoperative identification of risk factors for perioperative ABT in lung cancer surgery might help to reduce ABT use and improve surgery outcomes [ 6 ].…”
Section: Introductionmentioning
confidence: 99%