Blood Transfusion with Canine Blood in Two Cats with Hypovolemic Anemia

Sarpataki, Orsolya; Bedecean, Ioana; Codea, Razvan; Bel, Lucia; Cătană, R.; Marcus, Ioan; Sevastre, Bogdan

doi:10.15835/buasvmcn-vm:10622

Cited by 5 publications

(15 citation statements)

References 3 publications

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“…Several studies have reported successful outcome when canine blood was transfused to cats (1)(2)(3)(4)(5)(6)(7)(8)(9). No severe acute hemolysis or other adverse reactions were reported, leading to the assumption that cats were lacking strong naturally occurring antibodies against dog erythrocyte antigens (1-9).…”

Section: Xenotransfusionmentioning

confidence: 99%

“…Even though several studies did not report severe acute adverse reaction when cats were transfused with canine blood, non-fatal acute hemolytic reactions were recently described (1)(2)(3)(4)(5)(6)(7)(8)(9)(10). The rapid hemolysis following xenotransfusion suggested that naturally occurring antibodies against canine erythrocytes antigens were present in cats, the prevalence of these antibodies being higher in type A than in type B cats.…”

Section: Xenotransfusionmentioning

confidence: 99%

“…Based on a limited number of cases reported in the 1960s, cats do not appear to have naturally occurring antibodies against dog erythrocyte antigens, thereby potentially allowing xenotransfusion of canine blood to cats without inducing severe acute hemolytic reaction (1)(2)(3)(4)(5). In view of the limited availability of feline blood and the blood compatibility issues in cats, xenotransfusion has been successfully attempted as a life-saving procedure in a few cases (6)(7)(8)(9). Nevertheless, recent advances suggest that cats may actually have naturally occurring antibodies against dog erythrocyte antigens, and acute hemolytic reactions have been reported (10,11).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Life-Threatening Hemorrhage During Patent Ductus Arteriosus Ligation in a Cat: Xenotransfusion With Canine Blood

2020

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A 13-month-old Sphynx cat was referred for patent ductus arteriosus (PDA) ligation. A left thoracotomy was performed and the PDA was efficiently ligated. Immediately after chest tube placement, it presented extensive intrathoracic bleeding from the caudal intercostal artery. In view of the absolute necessity of a blood transfusion and given that compatible feline blood was not available, xenotransfusion of canine blood was administered to the cat and resulted in a positive outcome.

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Section: Xenotransfusionmentioning

confidence: 99%

Section: Xenotransfusionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Life-Threatening Hemorrhage During Patent Ductus Arteriosus Ligation in a Cat: Xenotransfusion With Canine Blood

2020

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“…For 46 years, from 1968 to 2014, no publication appeared; the practice was considered to be outdated. Only with Catherine Bovens’s review [ 5 ], which examined past successes, was xenotransfusion brought back from oblivion, and authors once again occasionally began to report a few cases: as of 2019, 17 have subsequently been described [ 6 , 7 , 8 , 9 , 10 , 11 , 12 ], in addition to two in vitro studies [ 13 , 14 ]. Only in 2020 did a large series consisting of 49 cases become more published [ 15 ].…”

Section: Introductionmentioning

confidence: 99%

Xenotransfusion of Blood from Dog to Cat: Should Canine Blood Be Our First Choice for Feline Transfusion in Emergency Situations?

Deschamps

Abboud

Roux

2022

Veterinary Sciences

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Despite the ability to determine feline blood types, the transfusion of canine blood to cats is still practiced in some countries. Xenotransfusion is effective—even if its effects only last for a few days—and is not associated with serious adverse effects. It avoids the need for blood typing, and most importantly, it avoids the transmission of intraspecific infectious agents, notably the feline leukemia virus (FeLV). Transfusion with canine blood is easier, quicker and less costly than transfusion with feline blood; it is less disagreeable for the donor. In the light of these arguments, when feline blood collected according to current guidelines is not available, in particular when the donor is not confirmed to be negative for the FeLV provirus, the authors consider it to be judicious to use canine blood for feline transfusion in emergency situations; this practice is preferable to inaction and to the inoculation of an infectious agent. Allotransfusion remains preferable in non-emergency situations as a treatment of chronic compensated anaemiae or if an appropriate donor (negative for FeLV provirus) is available. However, 2–4 days after a xenotransfusion, if a clinical alteration and a significant decrease in haematocrit are observed, a transfusion with cat’s blood confirmed to be negative for FeLV provirus should be performed. Xenotransfusion should never be used twice.

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“…1,2,7 Despite xenotransfusions being abandoned in all other domestic species since the early 1900s, transfusion of canine blood to cats is still performed in veterinary practice as a life-saving procedure when haemoglobinbased oxygen carrier solutions are not available and a suitable feline donor cannot be found. 5,[8][9][10] Based on a limited number of cases reported in the veterinary literature, with most publications dating from 1960s, cats did not appear to have naturally occurring antibodies against canine RBC antigens. 8 However, a recent study reported significant incompatibilities detected by XM tests between feline and canine blood.…”

Section: Introductionmentioning

confidence: 99%

Naturally occurring antibodies in cats against dog erythrocyte antigens and vice versa

Priolo

Masucci

Spada

et al. 2017

Journal of Feline Medicine and Surgery

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Objectives The aim of this study was to investigate the presence of naturally occurring antibodies against canine erythrocyte antigens in cats and vice versa. The influence of canine and feline blood type on cross-match results was also studied. Methods Blood samples from 34 cats and 42 dogs were used to perform test tube major and minor cross-match tests and blood typing. Blood from each cat was cross-matched with blood from 2-6 dogs, for a total of 111 cross-match tests. Haemolysis, macro- and microagglutination were considered markers of a positive cross-match. Results Eighty-three overall major cross-match tests were positive at 37°C, 86 at room temperature and 90 at 4°C. The minor cross-match tests were positive in all but two cross-matches performed at 37°C, all tests performed at room temperature and all but one test performed at 4°C. No cats tested totally negative at both major and minor cross-matches performed with samples from any single dog. Prevalence of warm natural antibodies against canine erythrocyte antigens was lower in type B cats than in type A cats, regardless of the blood type of donor dogs. Conclusions and relevance This study reveals a high prevalence of naturally occurring antibodies in cats against dog erythrocyte antigens and vice versa, and suggests that transfusion of cats with canine blood is not recommended as a routine procedure owing to the potential high risk of either acute severe or milder transfusion reactions.

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Blood Transfusion with Canine Blood in Two Cats with Hypovolemic Anemia

Cited by 5 publications

References 3 publications

Life-Threatening Hemorrhage During Patent Ductus Arteriosus Ligation in a Cat: Xenotransfusion With Canine Blood

Life-Threatening Hemorrhage During Patent Ductus Arteriosus Ligation in a Cat: Xenotransfusion With Canine Blood

Xenotransfusion of Blood from Dog to Cat: Should Canine Blood Be Our First Choice for Feline Transfusion in Emergency Situations?

Naturally occurring antibodies in cats against dog erythrocyte antigens and vice versa

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