Blood transfusion practices in Mwanza Region, Tanzania

Gumodoka, Balthazar; J, Vos; Kigadye, F. C.; Asten, Henri van; Dolmans, W.M.V.; Borgdorff, Martien W.

doi:10.1097/00002030-199303000-00013

Cited by 27 publications

(19 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…9 Usually, more than 70% of these transfusions are given to children aged less than 5 years. 4,11,12 Figures show that 2,050 (82.5%) of 2,482 children admitted to the medical paediatric wards of MNH between June 1998 and June 1999 received blood (unpublished report).…”

Section: Introductionmentioning

confidence: 99%

Post-transfusion hepatitis C seroprevalence in Tanzanian children

Kitundu

Msengi

Matee

et al. 2001

Annals of Tropical Paediatrics

View full text Add to dashboard Cite

In Tanzania, children with malaria-associated anaemia are frequently given blood transfusions, and donor blood is not screened for hepatitis C virus (HCV) infection. To determine the seroprevalence of HCV infection in Tanzanian children previously transfused with blood, 184 children (92 transfused, 92 not transfused) aged between 15 and 59 months matched for age and sex were screened for HCV antibodies by the particle agglutination test using Serodia anti-HCV (Fujirebio Inc., Japan). The overall prevalence of HCV infection was 7.1% (13/184). HCV seropositivity was 5.4% (5/92) among children with a history of blood transfusion and 8.6% (8/92) among the non-transfused. There was no significant difference in the prevalence of HCV infection between transfused and non-transfused children. None of the factors investigated, such as gender, the nutrition and HIV serostatus of the children and the marital and education status of their mothers, was associated with HCV seropositivity. Further studies are recommended to identify the factors associated with HCV infection in Tanzanian children.

show abstract

Section: Introductionmentioning

confidence: 99%

Post-transfusion hepatitis C seroprevalence in Tanzanian children

Kitundu

Msengi

Matee

et al. 2001

Annals of Tropical Paediatrics

View full text Add to dashboard Cite

show abstract

“…It is extremely important to note the high prevalence of HBsAg (8.7), HCV (1.6%) and syphilis (4.6%) and among HIV seronegative blood, which is normally deemed, fit for transfusion. These figures, which can be utilized to estimate the risk of transfusion associated transmission HBV, HCV and coinfections, should serve as a remainder to health personnel to take the necessary precautions, including reducing the number of unnecessary transfusions [23,24] .…”

Section: Discussionmentioning

confidence: 99%

Seroprevalence of Human Immunodeficiency Virus, Hepatitis Viruses, and Co-Infections among Blood Donors at Indore, Central India

O.P.Moorjani¹

2017

jmscr

View full text Add to dashboard Cite

show abstract

“…Numerous reports suggest that the number of transfu sions given unnecessarily in many African patient popula tions can be reduced considerably [10,11,13,16,17,[19][20][21][22], Other studies have more precisely defined the clinical in dications for blood transfusion in Africa [2,9,12]. In some cases, allogeneic blood transfusions can be avoided by the use of saline and autologous transfusions [21,31,38], An area greatly needing further research is identifying the most effective ways to change inappropriate blood transfusion practices in the region.…”

Section: Conclusion and Recommendationsmentioning

confidence: 99%

“…Many facilities performing transfu sions in Africa have been unable to establish antibody screening of donated blood [1][2][3][4][5][6][7][8]. Unnecessary use of blood in Africa continues [5,[9][10][11][12][13][14][15][16][17][18][19][20][21][22], Moreover, the efficacy of HIV risk factor exclusion strategies in Africa has been ques tioned [10,14,[23][24][25][26][27]. Finally, each of these strategies has limitations that are even more constraining due to specific features of the HIV epidemic in Africa.…”

Section: Introductionmentioning

confidence: 99%

Epidemiology and Prevention of Transfusion-Associated Human Immunodeficiency Virus Transmission in Sub-Saharan Africa

McFarland¹,

Moher²,

Shandera³

et al. 1997

Vox Sanguinis

View full text Add to dashboard Cite

Background and objectives: Compared to industrialised nations, countries in sub-Saharan Africa experience a greater amount of transfusion-associated HIV transmission due to high rates of transfusion in some groups of patients, a higher incidence and prevalence of HIV infection in donor populations, a lack of HIV antibody screening in some areas, and a higher residual risk of contamination in blood supplies despite antibody screening. Materials and methods: Epidemiologic review. Results: Epidemiologic evidence supports the effectiveness of three relatively inexpensive strategies to prevent transfusion-associated HIV transmission in sub-Saharan Africa: HIV antibody screening, avoidance of unnecessary use of blood products, and exclusion of donors at high risk of infection. Such prevention strategies have not been universally implemented. Conclusions: International aid to establish and maintain HIV antibody screening programmes, implementation of sound criteria for transfusion, and the search for HIV risk factors to use as donor exclusion criteria must be expanded in the region.

show abstract

Blood transfusion practices in Mwanza Region, Tanzania

Cited by 27 publications

References 0 publications

Post-transfusion hepatitis C seroprevalence in Tanzanian children

Post-transfusion hepatitis C seroprevalence in Tanzanian children

Seroprevalence of Human Immunodeficiency Virus, Hepatitis Viruses, and Co-Infections among Blood Donors at Indore, Central India

Epidemiology and Prevention of Transfusion-Associated Human Immunodeficiency Virus Transmission in Sub-Saharan Africa

Contact Info

Product

Resources

About