Blood Smear Profile of Patients With Dengue Hemorrhagic Fever in Bali Royal Hospital

Adnyana, I Made Dwi Mertha; Sudaryati, Ni Luh Gede; Suardana, A.A.K.

doi:10.20473/jvhs.v5.i1.2021.39-46

Cited by 3 publications

(4 citation statements)

References 19 publications

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“…Blood becomes an essential part of the darkness of human life (Adnyana et al, 2021). Patients with CKD who received PRC with incompatible results dominated by blood type O reached 27 people (12.85%).…”

Section: Discussionmentioning

confidence: 99%

Profile of Incompatible Reactions to Packed Red Cell Transfusion in Patients With Chronic Kidney Disease at Sanglah Hospital

2023

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Background: Since the prevalence of chronic renal failure disease has increased. Packed Red Cell (PRC) transfusions were a common way to replace the kidneys' function in filtration. However, the reaction caused was not widely reported. Purpose: To assess the profile of incompatible reactions in PRC transfusions of chronic kidney disease patients at Sanglah Hospital, Denpasar. Method: A descriptive observational study with a cross-sectional design was employed to identify incompatibility reactions in 210 patients using medical records from July–December 2021 at Sanglah Hospital in Denpasar. Sample determination using saturated sampling techniques and data analysis were carried out descriptively. Result: Incompatible reactions in patients with chronic renal failure at Sanglah Hospital Denpasar still affected 57 people (27.14%) out of 210 people with chronic renal failure. This condition could increase fatalities in various health services if not appropriately handled. Incompatible reactions could occur, and the higher risk was in patients of the male sex who were elderly (45–65 years), had blood type O, had hemoglobin (Hb) levels ranging from 6.1–9.0 g/dL, and had conducted PRC transfusions above three pouches with a frequency of more than three times. Conclusion: People with chronic kidney failure still had a high chance of having an incompatible reaction after a PRC transfusion. Many different things caused these reactions. Incompatibility reactions in people with chronic kidney failure should happen less often in the future if they were evaluated and found early.

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Section: Discussionmentioning

confidence: 99%

Profile of Incompatible Reactions to Packed Red Cell Transfusion in Patients With Chronic Kidney Disease at Sanglah Hospital

2023

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“…In addition, CRISPR technology helps reduce the dependence on insecticides, larvicides, pesticides, and other vector life-disrupting substances [74]. Traditional vector control methods, such as insecticides, larvicides, and pesticides, can have negative impacts on the environment and contribute to the development of resistance in broad-spectrum vectors that have harmful effects on nontarget organisms and ecosystems [83,84]. CRISPR-based interventions offer a more targeted and sustainable approach to vector control by identifying genes that have developed resistance, thereby reducing the reliance on these chemicals.…”

Section: Crispr-cas9-based Interventions Have the Potential To Modify...mentioning

confidence: 99%

CRISPR-Cas9 Genome Editing Technology for Zoonotic Disease Control in Indonesia: A Comprehensive Review

Adnyana,

Eljatin,

Sudaryati

et al. 2024

JMHT

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The increasing emergence of zoonotic diseases originating from vectors, rodents, mammals, and others has increased the potential for outbreaks of pandemics in the Indonesian territory. Although control and prevention have been implemented, these efforts have not yet revealed a bright spot; therefore, elaboration with advanced CRISPR-Cas9 technology is a way to accelerate efforts to control zoonotic diseases in Indonesia. However, there is limited literature on this topic. This review aims to comprehensively describe, identify, and summarize the application of CRISPR-Cas9 genome-editing technology in zoonotic disease control in Indonesia. Our findings show that CRISPR-Cas9 genome editing technology offers an innovative approach for zoonotic disease control by targeting disease vectors, modifying animal reservoirs, improving disease surveillance, enhancing vaccine development, and exploring traditional medicine candidates and immunotherapy. The high level of precision, efficiency, and versatility in targeting genomes capable of disrupting, damaging, and disrupting the disease transmission cycle in pathogens makes CRISPR-Cas9 highly effective. However, challenges such as off-target impacts, regulatory complexity, and ethical considerations must be overcome with inter- and multidisciplinary collaboration to promote transparency, equity, and public engagement throughout the process of implementing this technology in the field, especially in Indonesia.

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“…The incidence rate and case fatality rate both fluctuated significantly [1]. According to the report, the morbidity rate did not meet the national target of less than 49 per 100,000 population between 2018 to 2020 [1], [2]. This is because of many new instances discovered during the year.…”

Section: Dengue Hemorrhagic Fever Cases Were Discovered In Bali Betwe...mentioning

confidence: 99%

“…Based on health profile data in 2020, the number of incidents reached 12,173 cases, with an incidence rate of 280.7 and a case fatality rate of 0.2% (26 people) [1]. When viewed from 2018-to 2020, the number of dengue cases has increased three times from the previous year [2]. Furthermore, in the last decade, the province of Bali has been one of the top 10 contributors to the highest dengue hemorrhagic fever cases in Indonesia [3], [4].…”

Section: Introductionmentioning

confidence: 99%

Strategy to control and eradicate dengue hemorrhagic fever vectors in Bali

Adnyana

Surya²

2023

IJPHS

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Dengue hemorrhagic fever cases in Bali have increased in the past decade. Control and eradication efforts must be optimized. In order to create dengue-free zones, accurate information and a comprehensive strategy for accelerating dengue vector management are required. This paper is based on empirical, field, and epidemiological studies and program evaluations guided by the health belief model approach. In this regard, Bali's lesson on dengue cases fluctuated from 2018 to 2020. The incidence and death rates are increasing, especially during the COVID-19. Many factors affect the disease agent, the host, and the environment. The SIGAP strategy is a policy brief that is studied and implemented to accelerate dengue vector control in Bali, which includes: awareness of the importance of 4M-Plus (draining, closing, reusing used goods, and monitoring) and mosquito nest control; integration of dengue information services; using natural insecticides and larvicides; observing and reporting the presence of vectors to the larva monitoring officer; and regular monitoring weekly. Implementing the SIGAP strategy can reduce dengue vectors and speed up the process of getting rid of dengue disease in Bali.

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Blood Smear Profile of Patients With Dengue Hemorrhagic Fever in Bali Royal Hospital

Cited by 3 publications

References 19 publications

Profile of Incompatible Reactions to Packed Red Cell Transfusion in Patients With Chronic Kidney Disease at Sanglah Hospital

Profile of Incompatible Reactions to Packed Red Cell Transfusion in Patients With Chronic Kidney Disease at Sanglah Hospital

CRISPR-Cas9 Genome Editing Technology for Zoonotic Disease Control in Indonesia: A Comprehensive Review

Strategy to control and eradicate dengue hemorrhagic fever vectors in Bali

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