2000
DOI: 10.1007/s002280000208
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Blood pressure responses to whole-body cold exposure: effect of carvedilol

Abstract: Carvedilol reduced the BP during the cold exposure, especially in the hypertensive subjects but also in normotensive ones, without effect on the cold-induced rise of the BP.

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Cited by 24 publications
(20 citation statements)
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“…Carvedilol, 9 which was studied earlier in the same test procedures, decreased the level of BP slightly more than metoprolol, while the amount of cold-induced rise of BP was on the same level. The present results with mildly hypertensive subjects differ from previous studies with healthy subjects: DBP 11 and MAP 12 were higher with atenolol and propranolol compared to placebo and the amount of coldinduced rise was greater than with placebo during cold exposure.…”
Section: Dear Sirmentioning
confidence: 75%
See 2 more Smart Citations
“…Carvedilol, 9 which was studied earlier in the same test procedures, decreased the level of BP slightly more than metoprolol, while the amount of cold-induced rise of BP was on the same level. The present results with mildly hypertensive subjects differ from previous studies with healthy subjects: DBP 11 and MAP 12 were higher with atenolol and propranolol compared to placebo and the amount of coldinduced rise was greater than with placebo during cold exposure.…”
Section: Dear Sirmentioning
confidence: 75%
“…5,6 Both local and wholebody cold exposure increase BP. [7][8][9] In the northern part of the world, people are exposed to low outdoor temperatures while going to work and occasionally also during leisure time. Moreover, there are still many occupations involving part-or full-time outdoor work.…”
Section: Dear Sirmentioning
confidence: 99%
See 1 more Smart Citation
“…Whole body cold exposure (-15 1C and 3.5 m/s) with adequate winter clothing caused a rapid increase in blood pressure in mildly hypertensive subjects (Komulainen et al, 2000(Komulainen et al, , 2004. The cold-induced rise of blood pressure was maximally 28-34 (systolic, SBP) and 20-22 mmHg (diastolic, DBP).…”
Section: Introduction and Literaturementioning
confidence: 99%
“…This effect is attributed to a rise in parasympathetic activation of the heart following cold water immersion (Stanley et al, 2012). Increased parasympathetic activation reduces blood pressure during the cold pressor test (Komulainen et al, 2000).…”
Section: O N T R a C T I O Nmentioning
confidence: 99%