Blood Pressure Regulation and Vegetarian Diets

Berkow, Susan E.; Barnard, Neal D.

doi:10.1111/j.1753-4887.2005.tb00104.x

Cited by 95 publications

(38 citation statements)

References 71 publications

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“…An alteration to a vegetable-based diet is also efficacious to relieve hypertension (Berkow, Barnard, 2005). In this study, we explore the novel observation that antihypertensive effects of flavonoids in A. megalophylla are involved in affecting the remodeling, and the expressions of tumor suppressor genes and protooncogenes in vascular smooth muscle cells.…”

Section: Discussionmentioning

confidence: 99%

Total flavonoids from Ampelopsis megalophylla suppress proliferation of vascular smooth muscle cells in vivo and in vitro

Qiu

Zhou

et al. 2018

Braz. J. Pharm. Sci.

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Various benefits of flavonoids for ameliorating cardiovascular diseases have been demonstrated. However, the lowering effects on blood pressure caused by antiproliferative potentials of flavonoids in vascular smooth muscle cells are rare. In this study, the antihypertensive effects of total flavonoids from Ampelopsis megalophylla were investigated. The dynamic pressure values and the rate of media thickness versus lumen diameter were measured by the tail-cuff system and H&E staining in vivo, respectively. The mRNA expressions of ACE, Ang II, eNOS, c-Myc, cyclin D1 and p27Kip1 in thoracic aorta or A7r5 cells were measured by qPCR, respectively. The protein expressions of c-Myc, Cyclin D1, p27Kip1 and β-catenin in tissues or A7r5 cells were measured by Western blot assay. Total flavonoids of A. megalophylla (TFAM) reduced the expressions of ACE and Ang II, and elevated the content of eNOS in thoracic aorta cells of SHRs. Furthermore, TFAM decreased the mRNA and protein expressions of c-Myc and cyclin D1 by repressing the Wnt/β-catenin-mediated TCF/LEF transcriptional activation both in vivo and in vitro, which is synergetic with the up-regulation of p27Kip1 expression. Our study provided evidence for developing flavonoids from A. megalophylla as herbal supplements to prevent against cardiovascular diseases by suppressing vascular remodeling.

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Section: Discussionmentioning

confidence: 99%

Total flavonoids from Ampelopsis megalophylla suppress proliferation of vascular smooth muscle cells in vivo and in vitro

Qiu

Zhou

et al. 2018

Braz. J. Pharm. Sci.

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“…There are several studies showing that diets low in meat tend to give better health (e.g., Berkow and Barnard, 2005). However, because of the absence or extremely low content of vitamins B 12 and D, iron, selenium and zinc, a completely vegan diet presents nutritional problems, especially for individuals with high nutritional requirements, such as growing children.…”

Section: Published In Journal Ofmentioning

confidence: 99%

Animal Agriculture: Symbiosis, Culture, or Ethical Conflict?

Lund

Olsson

2006

J Agric Environ Ethics

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ABSTRACT. Several writers on animal ethics defend the abolition of most or all animal agriculture, which they consider an unethical exploitation of sentient non-human animals. However, animal agriculture can also be seen as a co-evolution over thousands of years, that has affected biology and behaviour on the one hand, and quality of life of humans and domestic animals on the other. Furthermore, animals are important in sustainable agriculture. They can increase efficiency by their ability to transform materials unsuitable for human consumption and by grazing areas that would be difficult to harvest otherwise. Grazing of natural pastures is essential for the pastoral landscape, an important habitat for wild flora and fauna and much valued by humans for its aesthetic value. Thus it seems that the environment gains substantially when animals are included in sustainable agriculture systems. But what about the animals themselves? Objections against animal agriculture often refer to the disrespect for animals' lives, integrity and welfare in present intensive animal production systems. Of the three issues at stake, neither integrity nor animal welfare need in principle be violated in carefully designed animal husbandry systems. The main ethical conflict seems to lie in the killing of animals, which is inevitable if the system is to deliver animal products. In this paper, we present the benefits and costs to humans and animals of including animals in sustainable agriculture, and discuss how to address some of the ethical issues involved.

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“…Although heredity plays a role in blood pressure variability, diet and lifestyle exert considerable influence in blood pressure regulation. [8] Earlier studies also suggest that non vegetarian diet leads to high blood pressure. [12] Blood pr Therefore this study was done to know how blood pressure is altered by aerobics exercise and yoga among hypertensive patients.…”

Section: This Is An Open Access Article Distributed Under the Creativmentioning

confidence: 99%