Blood Pressure Increase during Oxygen Supplementation in Chronic Kidney Disease Patients Is Mediated by Vasoconstriction Independent of Baroreflex Function

Bel, René van der; Caliskan, M.; Hulst, Rob A. van; Lieshout, Johannes J. van; Stroes, Erik S.G.; Krediet, C. T. Paul

doi:10.3389/fphys.2017.00186

Cited by 8 publications

(5 citation statements)

References 33 publications

(43 reference statements)

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“…The xBRS is a measure to quantify how much control the baroreflex has on the heart rate. The xBRS was calculated using beat-to-beat SBP and ReR interval in a sliding window of 10 s [36].…”

Section: Baroreceptor Sensitivitymentioning

confidence: 99%

Parenteral nutrition impairs plasma bile acid and gut hormone responses to mixed meal testing in lean healthy men

et al. 2021

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Background & aims: To investigate the acute effects of intravenous vs enteral meal administration on circulating bile acid and gut hormone responses. Methods: In a randomized crossover design, we compared the effects of duodenal (via a nasoduodenal tube) vs parenteral (intravenous) administration over 180 min of identical mixed meals on circulating bile acid and gut hormone concentrations in eight healthy lean men. We analysed the bile acid and gut hormone responses in two periods: the intraprandial period from time point (T) 0 until T180 during meal administration and the postprandial period from T180 until T360, after discontinuation of meal administration. Results: Intravenous meal administration decreased the intraprandial (AUC (mmol/L*min) duodenal 1469 ± 284 vs intravenous 240 ± 39, p < 0.01) and postprandial bile acid response (985 ± 240 vs 223 ± 5, p < 0.05) and was accompanied by decreased gut hormone responses including glucose-dependent insulinotropic polypeptide, glucagon-like peptide 1, glucagon-like peptide 2 and fibroblast growth factor 19. Furthermore, intravenous meal administration elicited greater glucose concentrations, but similar insulin concentrations compared to enteral administration. Conclusions: Compared to enteral administration, parenteral nutrition results in lower postprandial bile acid and gut hormone responses in healthy lean men. This was accompanied by higher glucose concentrations in the face of similar insulin concentrations exposing a clear incretin effect of enteral mixed meal administration. The alterations in bile acid homeostasis were apparent after only one intravenous meal.

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“…The xBRS is a measure to quantify how much control the baroreflex has on the heart rate. The xBRS was calculated using beat-to-beat SBP and ReR interval in a sliding window of 10 s [36].…”

Section: Baroreceptor Sensitivitymentioning

confidence: 99%

Parenteral nutrition impairs plasma bile acid and gut hormone responses to mixed meal testing in lean healthy men

et al. 2021

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“…Oxygen dissolved in plasma can pass through various atherosclerosis blockage, allowing ischemic conditions to be resolved (Rosyanti et al, 2019). Renal hypoxia is the underlying cause of CK progression and is associated with hypertension (Bel et al, 2017). In hypoxic conditions, cells that lack oxygen will carry out anaerobic metabolism or fermentation.…”

Section: The Role Of Hyperbaric Oxygen Therapy (Hbot) On Kidney Functionmentioning

confidence: 99%

“…A further study stated that the increment of blood pressure during HBOT was dose-dependent. Hemodynamic features such as SVR, heart rate, and cardiac output (CO) also increased (Bel et al, 2017). However, the underlying mechanism of this effect is still unknown.…”

Section: The Role Of Hyperbaric Oxygen Therapy (Hbot) On Kidney Functionmentioning

confidence: 99%

Effect of hyperbaric oxygen (HBO) therapy on kidney function in metabolic syndrome (MetS) patients

Hisnindarsyah

2023

SMJ IDI Surabaya

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Background: Hyperbaric Oxygen (HBO) therapy is the therapy of inhaling 100% pure oxygen in a hyperbaric chamber of more than 1 absolute atmosphere. Currently, the use of hyperbaric oxygen therapy is increasingly widespread, not only for decompression sickness and diving problems. But it has been used for clinical therapy, cosmetics, and geriatric care. The American Food and Drug Administration (FDA) has also confirmed various clinical indications, especially those related to metabolic syndromes such as Diabetes Mellitus (DM) and Diabetic Foot Ulcers (DFU). But the use of Hyperbaric Oxygen Therapy for kidney disease has not been fully study yet. Purpose: Here we summarized the scientific reason to use this therapy as adjuvant for patients with chronic kidney disease due to metabolic syndrome. Opinion: Several benefits of HBO has been reported such as reducing oxidative stress, alleviate vascular dysfunction and amyloid burden, ischemia and reperfusion injury, Increased NO production, and suggested to be useful as an adjuvant therapy in T2DM suspected with chronic kidney disease (CKD), as HBO therapy decrease the proteinuria by 50%. Renal hypoxia is the underlying causes of CK progression and associated hypertension. In hypoxic conditions, cells lack of oxygen, so that the cells carry out anaerobic metabolism or fermentation or Warburg effect. HBO therapy can assist in supplying oxygen more quickly at the cellular level (internal respiration), so that metabolism can re-process aerobically. Conclusion: HBO Therapy improves the patient's general condition in CKD with MetS, thereby preventing kidney disease complications. The effectiveness of HBOT for kidney disease still requires further research with a more frequent and longer treatment.

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“…Скорее всего, в сезонных модуляциях АД принимают участие хеморецепторы, реагирующие на количество кислорода, поступающего в организм. Во многих исследованиях было зафиксировано изменение уровня АД в условиях гипоксии и гипероксии [61,62]. Кроме того, обнаружено угнетающее действие кислорода на эндотелиальные вазодилататорные факторы -оксид азота и простагландины [63].…”

Section: материал и методыunclassified

The dependence of сircannual dynamics of blood pressure on seasonal fluctuations of meteorological and heliophysical factors. Meta-analysis

2019

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Many clinical studies have shown seasonal dynamics of blood pressure (BP), which most authors attribute to seasonal variations in air temperature. However, the fact that in the conditions of modern urban society the influence on the person of air temperature on the street is minimized, as well as the fact that the seasonal dynamics of BP is observed and in a tropical climate contradict this statement. It is known, that the length of the day, the atmospheric pressure, the relative humidity, geomagnetic activity are subject to seasonal dynamics. Studies have shown that fluctuations in these meteorological factors can cause change in blood pressure.Aim.To use meta-analysis of the results of studies, conducted in different climatic zones (from subarctic to tropical) and devoted to seasonal dynamics of BP, to determine which meteorological conditions most often corresponded to the annual maximum of BP and which to the annual minimum of BP.Material and methods. We selected 15 publications about seasonal dynamics of BP and seasonal exacerbations of arterial hypertension in 21 regions of the Northern Hemisphere of the Earth.Results.We confirmed that, in addition to air temperature, other factors are also subject to seasonal dynamics (atmospheric pressure, relative humidity, partial oxygen density in the air). No correlation was found between the amplitude of seasonal fluctuations in air temperature and the amplitude of seasonal fluctuations in BP. In addition, the amplitude of drcannual blood pressure fluctuations was greater in regions with a clear seasonal dynamics of the average monthly atmospheric pressure, compared with regions in which the this parameter does not have a clear seasonal dynamics. Also, in some regions, the seasonal maximum of BP coincided with high geomagnetic activity.Conclusion. According to the results, we concluded that seasonal fluctuations of BP are not a reaction of the cardiovascular system to seasonal dynamics of air temperature only. Most likely, seasonal fluctuations of BP are caused by changes in all meteorological factors that have seasonal dynamics.

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Blood Pressure Increase during Oxygen Supplementation in Chronic Kidney Disease Patients Is Mediated by Vasoconstriction Independent of Baroreflex Function

Cited by 8 publications

References 33 publications

Parenteral nutrition impairs plasma bile acid and gut hormone responses to mixed meal testing in lean healthy men

Parenteral nutrition impairs plasma bile acid and gut hormone responses to mixed meal testing in lean healthy men

Effect of hyperbaric oxygen (HBO) therapy on kidney function in metabolic syndrome (MetS) patients

The dependence of сircannual dynamics of blood pressure on seasonal fluctuations of meteorological and heliophysical factors. Meta-analysis

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