Blood Pressure in Andean Adults Living Permanently at Different Altitudes

Veloz, Andrés Fernando Vinueza; Riss, Aymaru Kailli Yaulema; Zeeuw, Chris I. De; Carpio-Arias, Tannia Valeria; Vinueza-Veloz, María Fernanda

doi:10.1089/ham.2019.0101

Cited by 3 publications

(2 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Compared to Mestizos, Amerindians had a lower chance of PreHTN, and being Afro-Ecuadorian/Mulato had a higher chance of PreHTN. Previous studies also identified that the rate of HTN was higher in Afro-Ecuadorians than in other ethnicities 34 , and at all altitudes indigenous people had lower SBP and DBP compared to Mestizos 35 , and Amerindians in Ecuador had low prevalence of atrial fibrillation, explained by racially determined short stature and frequent intake of oily fish in the diet 36 . The higher prevalence of PreHTN in men than women may be attributed to biological and social differences 37 .…”

Section: Discussionmentioning

confidence: 89%

National cross-sectional data on coexisting prehypertension and prediabetes among adults in Ecuador

Peltzer,

Pengpid

2023

Popul. Med.

View full text Add to dashboard Cite

INTRODUCTIONThe study aimed to estimate the prevalence and associated factors of coexisting prehypertension (PreHTN) and prediabetes (PreDM) among adults in Ecuador. METHODS Cross-sectional data from the Ecuador STEPS 2018 survey were analyzed for 3608 persons, aged 18-69 years (median: 39; IQR: 25), who had complete blood glucose and pressure data, were non-pregnant, without cardiovascular disease, and responded to interview and physical and biomedical measures. RESULTS Of the 3608 individuals, 247 (6.5%) had coexisting PreHTN and PreDM, 1353 (39.9%) had both normoglycemia and normotension, 823 (23.2%) had PreHTN only, and 321 (7.5%) had PreDM only. Compared to the group with both normoglycemia and normotension, older age (50-69 years), male sex, obesity, and elevated total cholesterol (TC) increased the risk, while having secondary education level decreased the risk of coexisting

show abstract

Section: Discussionmentioning

confidence: 89%

National cross-sectional data on coexisting prehypertension and prediabetes among adults in Ecuador

Peltzer,

Pengpid

2023

Popul. Med.

View full text Add to dashboard Cite

show abstract

“…Regarding the Tibetan population, it was found that altitude was U-shaped in its association with the likelihood of having hypertension [16]. Finally, in Ecuador, a non-linear J-shaped relationship was found between altitude and both SBP and DBP [41].…”

Section: Plos Onementioning

confidence: 94%

Hypertension subtypes at high altitude in Peru: Analysis of the Demographic and Family Health Survey 2016–2019

Ortiz-Saavedra,

Montes-Madariaga,

Moreno-Loaiza

et al. 2024

PLoS ONE

View full text Add to dashboard Cite

Background The prevalence of hypertension in Peru has increased over the years. Approximately one third of the Peruvian population lives at high altitudes. This population presents particular physiological, genetic and environmental characteristics that could be related to the prevalence of hypertension and its subtypes. Objective To assess the association between altitude and hypertension in the Peruvian population through an analysis of a nationally representative survey. Methods We conducted a cross-sectional analysis of the Demographic and Family Health Survey for the period 2016–2019. We included 122,336 individuals aged 18 years and older. Hypertension was defined according to the JNC-7 guidelines. High-altitude location was defined as a residential cluster located above 2,500 meters above sea level. We utilized generalized linear models from the Poisson family with a log-link function to assess the magnitude of the association between high altitude and hypertension. Additionally, we employed multinomial regression models to analyze the association between high altitude and subtypes of hypertension, including isolated systolic hypertension (ISH), isolated diastolic hypertension (IDH), and systolic-diastolic hypertension (SDH). Results In the adjusted Poisson regression model, we found that the prevalence of hypertension among participants living at high altitudes was lower compared to those living at low altitudes (aPR: 0.89; 95% CI: 0.86–0.93). In the adjusted multinomial regression model, we observed a lower prevalence rate of ISH among participants residing at high altitudes (aRPR: 0.68; 95% CI: 0.61–0.73) and a higher prevalence rate of IDH among participants residing at high altitudes (aRPR: 1.60; 95% CI: 1.32–1.94). Conclusions Residents at high altitudes in Peru have a lower prevalence rate of ISH and a higher prevalence rate of IDH compared to those living at low altitudes. Further studies are needed to determine the influence of other biological, environmental, and healthcare access factors on this relationship.

show abstract

Office and Ambulatory Arterial Hypertension in Highlanders

et al. 2020

View full text Add to dashboard Cite

Millions of people worldwide live at high altitude, being chronically exposed to hypobaric hypoxia. Hypertension is a major cardiovascular risk factor but data on its prevalence and determinants in highlanders are limited, and systematic studies with ambulatory blood pressure monitoring are not available. Aim of this study was to assess the prevalence of clinic and ambulatory hypertension and the associated factors in a sample of Andean highlanders. Hypertension prevalence and phenotypes were assessed with office and ambulatory blood pressure measurement in a sample of adults living in Cerro de Pasco, Peru (altitude 4340 m). Basic clinical data, blood oxygen saturation, hematocrit, and Qinghai Chronic Mountain Sickness score were obtained. Participants were classified according to the presence of excessive erythrocytosis and chronic mountain sickness diagnosis. Data of 289 participants (143 women, 146 men, mean age 38.3 years) were analyzed. Office hypertension was present in 20 (7%) participants, while ambulatory hypertension was found in 58 (20%) participants. Masked hypertension was common (15%), and white coat hypertension was rare (2%). Among participants with ambulatory hypertension, the most prevalent phenotypes included isolated nocturnal hypertension, isolated diastolic hypertension, and systodiastolic hypertension. Ambulatory hypertension was associated with male gender, age, overweight/obesity, 24-hour heart rate, and excessive erythrocytosis. Prevalence of hypertension among Andean highlanders may be significantly underestimated when based on conventional blood pressure measurements, due to the high prevalence of masked hypertension. In highlanders, ambulatory hypertension may be independently associated with excessive erythrocytosis.

show abstract

Blood Pressure in Andean Adults Living Permanently at Different Altitudes

Cited by 3 publications

References 24 publications

National cross-sectional data on coexisting prehypertension and prediabetes among adults in Ecuador

National cross-sectional data on coexisting prehypertension and prediabetes among adults in Ecuador

Hypertension subtypes at high altitude in Peru: Analysis of the Demographic and Family Health Survey 2016–2019

Office and Ambulatory Arterial Hypertension in Highlanders

Contact Info

Product

Resources

About