Blood-pressure control in the hypertensive population

Mancia, Giuseppe; Sega, Roberto; Milesi, C; Cessna, Giancarlo; Zanchetti, Alberto

doi:10.1016/s0140-6736(96)07099-7

Cited by 254 publications

(135 citation statements)

References 11 publications

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“…[10][11][12][13][14] In particular, some hypertensive patients do not exhibit the normal nocturnal BP fall, and they have been called 'non-dippers', whereas those with normal circadian rhythm have been called 'dippers'. [15][16][17][18] Moreover, studies that used AMBP showed that the reduction in night time BP seems to lower in secondary forms of hypertension. [17][18][19][20][21] The aim of our study was to assess the behaviour of BP by ABPM in patients with PHPT, evaluating the prevalence of hypertension and the 'dipper' phenomenon.…”

Section: Introductionmentioning

confidence: 99%

Ambulatory monitoring of blood pressure (AMBP) in patients with primary hyperparathyroidism

et al. 2005

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The purpose of our study was to evaluate the behaviour of blood pressure (BP) by ambulatory monitoring of blood pressure (AMBP) in 53 patients with primary hyperparathyroidism (PHPT) compared to 100 essential hypertensive (EH) and 31 healthy subjects (HS). The correlations between calcium-phosphorus metabolism and haemodynamic parameters in all groups are included in the study. AMBP was performed using the oscillometric technique (Space-Labs, 90207, Redmond, WA, USA) and the following AMBP parameters were evaluated: average day time systolic (S) and diastolic (D) blood pressure (BP) and heart rate (HR) (when awake), average night time SBP, DBP and HR (when asleep) and average 24-h-SBP, DBP and HR. The definition of 'dipper' or 'non-dipper' subjects was established if night time SBP and DBP fall was 410% and o10%, respectively. In total, 25 PHPT patients (47.2%) were hypertensive (HT-PHPT) and 28 PHPT (52.8%) were normotensive (NT-PHPT). Mean 24-h-SBP and DBP obtained by AMBP was higher in HT-PHPT (Po0.05) and EH (Po0.05) than in NT-PHPT and HS. The multiple linear regression has shown that in PHPT-HT patients ionized calcium is an independent factor for the rise of 24-h-DBP values (r: 0.497; Po0.05) and daytime DBP values (r: 0.497; Po0.05). In 56% of HT-PHPT patients there is an absence of physiological BP nocturnal fall ('non-dipper'), which is statistically significant (Po0.05) compared with 'nondipper' EH patients (30%). In conclusion, in our study the prevalence of hypertension in PHPT was 47%. AMBP revealed that the 'non-dipping 'pattern was much higher in HT-PHPT patients in respect to EH patients.

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Section: Introductionmentioning

confidence: 99%

Ambulatory monitoring of blood pressure (AMBP) in patients with primary hyperparathyroidism

et al. 2005

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“…[1][2][3] In clinical practice, however, the use of antihypertensive drugs is often inadequate in terms of the numbers of patients treated and in terms of treatment adherence. [4][5][6][7] This means that blood pressure (BP) values are not controlled sufficiently by drug treatment. 8 Fifty general practitioners in the Ravenna area, Italy, voluntarily participated in the PANDORA project, a prospective on-going global outcomes study begun in 1996 to organize an electronic database to be used in pharmaco-epidemiological evaluations aimed at improving clinical practice.…”

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confidence: 99%

Adherence to antihypertensive drug treatment and blood pressure control: a real practice analysis in Italy

et al. 2007

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“…The prevalence of well-treated hypertensives is similar to that observed in other countries, like US in the NHANES, 18 and also in other Italian areas, like in the city of Monza where it averaged 28%. 19 It is interesting to stress, however, that the comparison of the BP measurements made in our patients in 1983-1985 and 1989-1992 indicates that BP control markedly improved, with a significant reduction by À13/À7 mmHg in SBP and DBP values in Group 3 and a slight BP reduction in Group 4 (À1/À4 mmHg). Patients who did not receive antihypertensive drugs, on the other hand, showed an increase in their BP by 13/2.5 mmHg.…”

Section: Discussionmentioning

confidence: 60%

Arterial hypertension increases left ventricular mass: role of tight blood pressure control

Ferrara¹,

Vaccaro²,

Cardoni³

et al. 2004

J Hum Hypertens

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In middle-age hypertensives from the Gubbio Population Study, we evaluated the relationship between blood pressure (BP) control over a long time and the prevalence of left ventricular hypertrophy (LVH). A population survey was performed in 1982-1985 and repeated in 1989-1992. During the second survey, subjects in the age range 40-60 years were invited to undergo an M-mode echocardiographic examination. A total of 487 subjects who participated in both surveys are included in the present analysis. Some of them (294) were normotensive (Group 1), 110 were hypertensive but had never taken antihypertensive drugs (Group 2), 47 hypertensives on drugs were in good BP control (Group 3) and 36 hypertensives on drugs had uncontrolled hypertension (Group 4). BP values at the 1989-1992 examination were, respectively, 122/77, 145/86, 124/ 78 and 153/91 mmHg, while 7 years earlier were 122/77, 133/84, 136/85 and 152/95 mmHg. Despite normal BP levels in Group 3, left ventricular mass index (LVMi, g/ m 2.7 ) was greater than in normotensives (42.4710, 46.6713, 47.0710, 51.9715 g/m 2.7 ). Accordingly, the prevalence of LVH (LVMi 451 g/m 2.7 ) was 18, 26.4, 36.7 and 50% in groups 1-4, respectively. The 193 hypertensives were, thereafter, divided according to BP control (ie o140/90 mmHg) on both surveys (1983-1985 and 1989-1992): 27 hypertensives with optimal BP levels on both visits also had a ventricular mass similar to normotensives and significantly lower than the other hypertensives (LVMi 44.6711.6 vs 48.5713.2, Po0.001).In conclusion, these findings indicate that hypertensive patients with BP values at levels similar to those in normotensives for a long period do not increase their left ventricular mass in comparison to subjects with normal BP levels.

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Blood-pressure control in the hypertensive population

Cited by 254 publications

References 11 publications

Ambulatory monitoring of blood pressure (AMBP) in patients with primary hyperparathyroidism

Ambulatory monitoring of blood pressure (AMBP) in patients with primary hyperparathyroidism

Adherence to antihypertensive drug treatment and blood pressure control: a real practice analysis in Italy

Arterial hypertension increases left ventricular mass: role of tight blood pressure control

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