Blood Pressure and Serum Parathyroid Hormone Level

Tena, Jaime García de; Hernández-Gutiérrez, Cristina; Abejón-López, Laura

doi:10.1001/jamainternmed.2015.0760

Cited by 1 publication

(1 citation statement)

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“…Our study found that serum phosphorus and iPTH were positively correlated with VIMSBP. Moreover, growing lines of evidence from the recent studies have illustrated that elevated phosphate can promote vascular calcification, endothelia dysfunction, and arterial stiffness (23)(24)(25)(26). As is suggested by data analysis from the National Health and Nutrition Examination Survey (NHANES) cohort, serum iPTH levels were significantly positively correlated with both SBP and DBP (27).…”

Section: Discussionmentioning

confidence: 96%

Blood pressure variability is independent of systolic pressure in adolescent and young adult patients undergoing hemodialysis

Zhang

Shen

et al. 2018

Pediatr Res

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BackgroundPre-dialysis blood pressure variability (BPV) in adolescent and young-adult maintenance hemodialysis (MHD) patients remains unknown. This study aimed to show the degree of 44-h BPV and to explore its related risk factors in adolescent and young-adult MHD patients.MethodsOne hundred and fifty-three hemodialysis patients aged from 14 to 29 were selected from 11 medical facilities in Guizhou, China. Variability independent of the mean BP (VIM) obtained by 44-h ambulatory BP monitoring was used to calculate BPV. Baseline characteristics, physical measurement, and laboratory parameters were compared between different groups categorized by quartiles of VIM of systolic BP (VIMSBP).ResultsVIMSBP levels were found to be positively related to interdialytic weigh growth rate (IDWG), serum phosphorus, and serum intact parathyroid hormone (iPTH; Spearman correlation coefficients 0.474, 0.229, and 0.437, respectively; P<0.05 for all) and negatively related to hemoglobin (Hb) and albumin (-0.317, P<0.001, and -0.166, P=0.04, respectively) in all adolescent and young-adult MHD patients. In multiple linear regression analysis, IDWG, Hb, serum phosphorus, and serum iPTH had an independent association with VIMSBP.ConclusionOur analysis revealed an independent association of BPV with IDWG, Hb, serum phosphorus, and serum iPTH among adolescent and young-adult patients undergoing dialysis. This observation warrants further study.

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