“…This is contrary to our study. 9 Our findings of haemodynamic response to extubation attenuated by esmolol are consistent & comparable to study conducted by Muzzi DA, Black S, et al 10 They compared efficacy of esmolol and labetalol in treating increase in blood pressure during emergence and recovery from anaesthesia after intracranial surgery. They found both esmolol and labetalol were equally effective in controlling systolic blood pressure on emergence and in the recovery room in patients undergoing intracranial surgery.…”
Section: About Systolic and Diastolic Bp Changessupporting
“…This is contrary to our study. 9 Our findings of haemodynamic response to extubation attenuated by esmolol are consistent & comparable to study conducted by Muzzi DA, Black S, et al 10 They compared efficacy of esmolol and labetalol in treating increase in blood pressure during emergence and recovery from anaesthesia after intracranial surgery. They found both esmolol and labetalol were equally effective in controlling systolic blood pressure on emergence and in the recovery room in patients undergoing intracranial surgery.…”
Section: About Systolic and Diastolic Bp Changessupporting
“…Though there were no electrocardiographic evidences, these may be secondary to myocardial ischemia. 11 The changes were transient and subsided two minutes after NTG spray. However, blood pressure needed to be controlled with esmolol.…”
Background: The present study was undertaken to evaluate efficacy of nitroglycerine (NTG) spray for attenuating haemodynamic response to tracheal extubation in normotensive and hypertensive patients.Methods: The study enrolling total 120 ASA I and II patients, (60 normotensive and 60 hypertensive) who had undergone elective surgery under general endotracheal anaesthesia. Both these types of patients were randomly subdivided into two groups of 30 patients each -50% receiving NTG spray and 50% not receiving NTG spray.Results: There was significant increase in heart rate in all four groups after NTG spray. During extubation this increased in heart rate was not statistically significant in group A (Normotensive with NTG) but was significant in group C (hypertensive with NTG) when compared with control groups. Similarly, during extubation there was significant rise in systolic, diastolic and mean arterial blood pressure were noted in all four groups and with use of NTG spray the increase could be significantly attenuated in NTG groups. Increase in heart rate along with reduction in blood pressure seen after NTG spray did not produce significant increase in RPP as compared to hypertensive and normotensive patients who did not receive the NTG spray.Conclusions: Sublingually administered nitroglycerin spray in a dose of 0.8 mg prior to extubation is an effective, practical, easy and relatively safe method in attenuate haemodynamic response to tracheal extubation.
“…Endotracheal extubation is done in lighter plane of anaesthesia which produces a significant increase in heart rate and blood pressure which persists into the recovery period [3][4][5]. Even this transient increase in heart rate and blood pressure is a matter of concern in patients with cardiovascular diseases as it may lead to left ventricular failure, cerebrovascular accidents and intracranial hypertension [6].…”
Introduction: Airway management is an essential, but challenging skill in the field of anaesthesiology. Since many years, endotracheal tube has been in vogue for surgeries involving general anaesthesia. However, endotracheal extubation causes serious hemodynamic changes, which could result in several cardiovascular complications. Among several advanced techniques, Laryngeal Mask Airway (LMA) is a less invasive procedure, with similar therapeutic outcomes. This study was carried out to compare the hemodynamic responses between LMA and endotracheal tube extubation.
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